دورية أكاديمية
Contribution of the anaerobic blood culture vial for the recovery of Candida glabrata : A retrospective multicentric study
| العنوان: | Contribution of the anaerobic blood culture vial for the recovery of Candida glabrata : A retrospective multicentric study |
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| المؤلفون: | Farfour, Eric, Le Brun, Cecile, Mizrahi, Assaf, Bargain, Pauline, Durieux, Marie-Fleur, Boquel, Frédérique, Corvec, Stéphane, Jeddi, Fakhri, Muggeo, Anaëlle, Huguenin, Antoine, Barraud, Olivier, Amara, Marlène, Fihman, Vincent, Bailly, Eric, Botterel, Françoise, Guillard, Thomas, Vasse, Marc, Guillouzouic, Aurélie, d'Epenoux, Louise Ruffier, Bémer, Pascale, Juvin, Marie-Emmanuelle, Woerther, Paul-Louis, Foulet, Francoise, Ammar, Nawel Ait, Le Pape, Patrice, Villena, Isabelle, Des Champs, Christophe, Mereghetti, Laurent, Desoubeaux, Guillaume, Le Monnier, Alban, Ajzenberg, Daniel, Maneglier, Benjamin |
| المساهمون: | Hôpital Foch Suresnes, Service de Bactériologie-Virologie-Hygiène Tours, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau, Centre hospitalier Saint-Joseph Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hopital A.-Mignot, CHU Limoges, CHU Henri Mondor Créteil, Immunology and New Concepts in ImmunoTherapy (INCIT), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Cibles et Médicaments des Infections et de l'Immunité (IICiMed), Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Pathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 (P3CELL), Université de Reims Champagne-Ardenne (URCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital universitaire Robert Debré Reims (CHU Reims), Epidémiosurveillance de protozooses à transmission alimentaire et vectorielle (ESCAPE), Université de Reims Champagne-Ardenne (URCA)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Centre d'Investigation Clinique de Limoges (CIC1435), CHU Limoges-Institut National de la Santé et de la Recherche Médicale (INSERM), Anti-infectieux : supports moléculaires des résistances et innovations thérapeutiques (RESINFIT), CHU Limoges-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Centre Hospitalier de Versailles André Mignot (CHV), CHU Trousseau Tours, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Dynamic Microbiology - EA 7380 (DYNAMIC), École nationale vétérinaire d'Alfort (ENVA)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université Paris-Est (UPE)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hémostase, Inflammation, Thrombose (HITH - U1176 Inserm - CHU Bicêtre), Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Saclay, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Hôtel-Dieu de Nantes, Université Paris-Saclay, Groupe Hospitalier Paris Saint-Joseph (hpsj) |
| المصدر: | ISSN: 1369-3786. |
| بيانات النشر: | HAL CCSD Oxford University Press |
| سنة النشر: | 2022 |
| المجموعة: | Anses: HAL (Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail) |
| مصطلحات موضوعية: | [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| الوصف: | International audience ; Abstract Although Candida spp are aerobic microorganisms, some Candida strains, mainly Candida glabrata, can be recovered from anaerobic blood culture vials. We assessed the contribution of the anaerobic vials for the diagnosis of candidemia, especially for C. glabrata. We conducted a multicenter retrospective study including eight university or regional hospitals. A single episode of monomicrobial candidemia per patient was included from September 1st, 2016, to August 31st, 2019. The characteristics of all aerobic and anaerobic blood culture vials sampled within 2 h before and after the first positive blood culture vials were recorded (type of vials, result, and for positive vials time-to-positivity and Candida species). Overall, 509 episodes of candidemia were included. The main species were C. albicans (55.6%) followed by C. glabrata (17.1%), C. parapsilosis (4.9%), and C. tropicalis (4.5%). An anaerobic vial was positive in 76 (14.9%) of all episodes of which 56 (73.8%) were due to C. glabrata. The number of C. glabrata infections only positive in anaerobic vials was 1 (2.6%), 1 (11.1%), and 15 (37.5%) with the BACT/ALERT 3D the BACT/ALERT VIRTUO and the BACTEC FX instrument, respectively (P < 0.01). The initial positivity of an anaerobic vial was highly predictive of the isolation of C. glabrata with the BACTEC FX (sensitivity of 96.8%). C. glabrata time-to-positivity was shorter in anaerobic vial than aerobic vial with all instruments. Anaerobic blood culture vials improve the recovery of Candida spp mainly C. glabrata. This study could be completed by further analyses including mycological and pediatric vials. Lay summary Although Candida spp are aerobic microorganisms, C. glabrata is able to grow in anaerobic conditions. In blood culture, the time-to-positivity of C. glabrata is shorter in anaerobic than aerobic vials. Only the anaerobic vial was positive in up to 15 (37.5%) C. glabrata bloodstream infections. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-04316567; https://hal.science/hal-04316567Test |
| DOI: | 10.1093/mmy/myac021 |
| الإتاحة: | https://doi.org/10.1093/mmy/myac021Test https://hal.science/hal-04316567Test |
| رقم الانضمام: | edsbas.B15BBFB5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/mmy/myac021 |
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