التفاصيل البيبلوغرافية
| العنوان: |
Recent advances in the potential role of RNA N4-acetylcytidine in cancer progression |
| المؤلفون: |
Zhang, Shujun, Liu, Yafeng, Ma, Xiao, Gao, Xiaohui, Ru, Yi, Hu, Xinjun, Gu, Xinyu |
| المصدر: |
Cell Communication and Signaling ; volume 22, issue 1 ; ISSN 1478-811X |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2024 |
| مصطلحات موضوعية: |
Cell Biology, Molecular Biology, Biochemistry |
| الوصف: |
N 4 -acetylcytidine (ac 4 C) is a highly conserved chemical modification widely found in eukaryotic and prokaryotic RNA, such as tRNA, rRNA, and mRNA. This modification is significantly associated with various human diseases, especially cancer, and its formation depends on the catalytic activity of N-acetyltransferase 10 (NAT10), the only known protein that produces ac 4 C. This review discusses the detection techniques and regulatory mechanisms of ac 4 C and summarizes ac 4 C correlation with tumor occurrence, development, prognosis, and drug therapy. It also comments on a new biomarker for early tumor diagnosis and prognosis prediction and a new target for tumor therapy. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1186/s12964-023-01417-5 |
| DOI: |
10.1186/s12964-023-01417-5.pdf |
| DOI: |
10.1186/s12964-023-01417-5/fulltext.html |
| الإتاحة: |
https://doi.org/10.1186/s12964-023-01417-5Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.B1577055 |
| قاعدة البيانات: |
BASE |
