دورية أكاديمية
Laryngopharyngeal reflux diagnosis in obstructive sleep apnea patients using the pepsin salivary test
| العنوان: | Laryngopharyngeal reflux diagnosis in obstructive sleep apnea patients using the pepsin salivary test |
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| المؤلفون: | Iannella G., Vicini C., Polimeni A., Greco A., Gobbi R., Montevecchi F., De Vito A., Meccariello G., Cammaroto G., D'Agostino G., Pace A., Cascella R., Brunori M., Lo Iacono C. A. M., Pelucchi S., Magliulo G. |
| المساهمون: | Iannella, G., Vicini, C., Polimeni, A., Greco, A., Gobbi, R., Montevecchi, F., De Vito, A., Meccariello, G., Cammaroto, G., D'Agostino, G., Pace, A., Cascella, R., Brunori, M., Lo Iacono, C. A. M., Pelucchi, S., Magliulo, G. |
| سنة النشر: | 2019 |
| المجموعة: | Università degli Studi di Ferrara: CINECA IRIS |
| مصطلحات موضوعية: | Laryngopharyngeal reflux, Obstructive sleep apnea, Obstructive Sleep Apnea Syndrome, PEP-test, Adult, Body Mass Index, Employment, Female, Human, Linear Model, Male, Middle Aged, Pepsin A, Saliva, Sleep Apnea, Obstructive |
| الوصف: | Background: To investigate the presence of laryngopharyngeal reflux in patients with obstructive sleep apnea (OSA) employing the salivary pepsin concentration method. To compare the results of pepsin concentration with the severity of the pathology. Methods: Seventy-five OSA patients (44 males, 31 females) were enrolled in the study. For each patient, the AHI (apnea–hypopnea index) and the BMI (body mass index) were initially evaluated. All the patients enrolled were assessed using the reflux symptom index (RSI) and the reflux finding score (RFS) in order to perform a clinical diagnosis of laryngopharyngeal reflux. In all patients a salivary sample was taken to estimate the presence of pepsin and its concentration. Results: The incidence of LPR (laryngopharyngeal reflux) in OSA patients, evaluated using the salivary pepsin concentration test (PEP-test), was found to be 32% of cases. Linear regression testing did not show any correlation between AHI and pepsin concentration in salivary samples (p = 0.1). Conclusion: A high number of patients with OSA seem to show positivity for salivary pepsin, correlated to an LPR. There does not appear to be a correlation between the severity of apnea and the grade of salivary pepsin reflux. On the other hand, direct correlation between BMI and the value of pepsin in salivary specimens was observed. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31185704; info:eu-repo/semantics/altIdentifier/wos/WOS:000472132900184; volume:16; issue:11; firstpage:2056-1; lastpage:2056-10; numberofpages:10; journal:INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; http://hdl.handle.net/11392/2413062Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85067799368; https://www.mdpi.com/1660-4601/16/11/2056/pdfTest; https://www.mdpi.com/1660-4601/16/11/2056Test |
| DOI: | 10.3390/ijerph16112056 |
| الإتاحة: | https://doi.org/10.3390/ijerph16112056Test http://hdl.handle.net/11392/2413062Test https://www.mdpi.com/1660-4601/16/11/2056/pdfTest https://www.mdpi.com/1660-4601/16/11/2056Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B11D17CD |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/ijerph16112056 |
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