التفاصيل البيبلوغرافية
| العنوان: |
Successful healing of non-healing surgical wound based on the release of platelet-derived growth factors from single donor allogeneic platelet-RICH plasma with one freeze-thaw cycle: a case report after a 1-year follow-up |
| المؤلفون: |
Seco-Calvo, Jesús, Vidán-Estévez, Julia, Sánchez-Herráez, Sergio |
| المصدر: |
Translational Medicine Communications ; volume 7, issue 1 ; ISSN 2396-832X |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2022 |
| الوصف: |
Background Non-healing surgical wounds is a risk in certain patients. Recently, allogenic plasma-rich-platelet (PRP) is used such as regenerative treatment of different non-healing surgical wounds. Purpose We explore the potential role of using platelet-derived growth factors from single donor PRP, with a freeze-thaw process, for the treatment of surgical scar ulcer. Methods We have used a PRP preparation protocol that involved a single cycle of centrifugation at a mean speed of 2400–2800 rpm of donor blood taken with an apheresis machine. Results To our knowledge, this is the first study using the platelet-derived growth factors (PDGF) from single donor apheresis, with a freeze-thaw process. Four weeks after daily application of al-PRP, the ulcer progressed satisfactorily; at six weeks, the ulcer had healed. Conclusion We concluded that the healing of a surgical wound observed in our case, is promising and suggests that al-PRP might play a role in treating surgical scar ulcers. This must be confirmed in future studies. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1186/s41231-022-00120-w |
| DOI: |
10.1186/s41231-022-00120-w.pdf |
| DOI: |
10.1186/s41231-022-00120-w/fulltext.html |
| الإتاحة: |
https://doi.org/10.1186/s41231-022-00120-wTest |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.B0A682EA |
| قاعدة البيانات: |
BASE |
