دورية أكاديمية
Outcomes in people with eating disorders:a transdiagnostic and disorder-specific systematic review, meta-analysis and multivariable meta-regression analysis
| العنوان: | Outcomes in people with eating disorders:a transdiagnostic and disorder-specific systematic review, meta-analysis and multivariable meta-regression analysis |
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| المؤلفون: | Solmi, Marco, Monaco, Francesco, Højlund, Mikkel, Monteleone, Alessio M., Trott, Mike, Firth, Joseph, Carfagno, Marco, Eaton, Melissa, De Toffol, Marco, Vergine, Mariantonietta, Meneguzzo, Paolo, Collantoni, Enrico, Gallicchio, Davide, Stubbs, Brendon, Girardi, Anna, Busetto, Paolo, Favaro, Angela, Carvalho, Andre F., Steinhausen, Hans Christoph, Correll, Christoph U. |
| المصدر: | Solmi , M , Monaco , F , Højlund , M , Monteleone , A M , Trott , M , Firth , J , Carfagno , M , Eaton , M , De Toffol , M , Vergine , M , Meneguzzo , P , Collantoni , E , Gallicchio , D , Stubbs , B , Girardi , A , Busetto , P , Favaro , A , Carvalho , A F , Steinhausen , H C & Correll , C U 2024 , ' Outcomes in people with eating disorders : a transdiagnostic and disorder-specific systematic .... |
| سنة النشر: | 2024 |
| المجموعة: | King's College, London: Research Portal |
| مصطلحات موضوعية: | anorexia nervosa, binge eating disorder, bulimia nervosa, chronicity, cognitive-behavioral therapy, diagnostic migration, Eating disorders, family-based therapy, hospitalization, mortality, nutritional interventions, recovery |
| الوصف: | Eating disorders (EDs) are known to be associated with high mortality and often chronic and severe course, but a recent comprehensive systematic review of their outcomes is currently missing. In the present systematic review and meta-analysis, we examined cohort studies and clinical trials published between 1980 and 2021 that reported, for DSM/ICD-defined EDs, overall ED outcomes (i.e., recovery, improvement and relapse, all-cause and ED-related hospitalization, and chronicity); the same outcomes related to purging, binge eating and body weight status; as well as mortality. We included 415 studies (N=88,372, mean age: 25.7±6.9 years, females: 72.4%, mean follow-up: 38.3±76.5 months), conducted in persons with anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), other specified feeding and eating disorders (OSFED), and/or mixed EDs, from all continents except Africa. In all EDs pooled together, overall recovery occurred in 46% of patients (95% CI: 44-49, n=283, mean follow-up: 44.9±62.8 months, no significant ED-group difference). The recovery rate was 42% at <2 years, 43% at 2 to <4 years, 54% at 4 to <6 years, 59% at 6 to <8 years, 64% at 8 to <10 years, and 67% at ≥10 years. Overall chronicity occurred in 25% of patients (95% CI: 23-29, n=170, mean follow-up: 59.3±71.2 months, no significant ED-group difference). The chronicity rate was 33% at <2 years, 40% at 2 to <4 years, 23% at 4 to <6 years, 25% at 6 to <8 years, 12% at 8 to <10 years, and 18% at ≥10 years. Mortality occurred in 0.4% of patients (95% CI: 0.2-0.7, n=214, mean follow-up: 72.2±117.7 months, no significant ED-group difference). Considering observational studies, the mortality rate was 5.2 deaths/1,000 person-years (95% CI: 4.4-6.1, n=167, mean follow-up: 88.7±120.5 months; significant difference among EDs: p<0.01, range: from 8.2 for mixed ED to 3.4 for BN). Hospitalization occurred in 26% of patients (95% CI: 18-36, n=18, mean follow-up: 43.2±41.6 months; significant difference among EDs: ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/wps.21182 |
| الإتاحة: | https://doi.org/10.1002/wps.21182Test https://kclpure.kcl.ac.uk/portal/en/publications/7e705110-e411-4ca8-a267-891708656240Test http://www.scopus.com/inward/record.url?scp=85182166588&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B082D8E9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/wps.21182 |
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