دورية أكاديمية
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
| العنوان: | Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 |
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| المؤلفون: | Sant-Rayn Pasricha, Pei Jin Lim, Tiago L. Duarte, Carla Casu, Dorenda Oosterhuis, Katarzyna Mleczko-Sanecka, Maria Suciu, Ana Rita Da Silva, Kinda Al-Hourani, João Arezes, Kirsty McHugh, Sarah Gooding, Joe N. Frost, Katherine Wray, Ana Santos, Graça Porto, Emmanouela Repapi, Nicki Gray, Simon J. Draper, Neil Ashley, Elizabeth Soilleux, Peter Olinga, Martina U. Muckenthaler, Jim R. Hughes, Stefano Rivella, Thomas A. Milne, Andrew E. Armitage, Hal Drakesmith |
| المصدر: | Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
| بيانات النشر: | Nature Portfolio |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Science |
| الوصف: | Hepcidin controls systemic iron levels by inhibiting intestinal iron absorption and iron recycling. Here, Pasricha et al. demonstrate that the hepcidin-chromatin locus displays HDAC3-mediated reversible epigenetic modifications during both erythropoiesis and iron deficiency. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2041-1723 |
| العلاقة: | https://doi.org/10.1038/s41467-017-00500-zTest; https://doaj.org/toc/2041-1723Test; https://doaj.org/article/15032712babd4934b8cf9987f86cc0baTest |
| DOI: | 10.1038/s41467-017-00500-z |
| الإتاحة: | https://doi.org/10.1038/s41467-017-00500-zTest https://doaj.org/article/15032712babd4934b8cf9987f86cc0baTest |
| رقم الانضمام: | edsbas.B01EF266 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20411723 |
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| DOI: | 10.1038/s41467-017-00500-z |