تقرير
Amygdala hyperactivation relates to eating behavior: a potential indicator of food addiction in Prader-Willi syndrome
| العنوان: | Amygdala hyperactivation relates to eating behavior: a potential indicator of food addiction in Prader-Willi syndrome |
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| المؤلفون: | Strelnikov, Kuzma, Debladis, Jimmy, Salles, Juliette, Valette, Marion, Cortadellas, Julie, Tauber, Maithé, Barone, Pascal |
| المساهمون: | Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre de recherche cerveau et cognition (CERCO UMR5549), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Référence du Syndrome de Prader-Willi CHU Toulouse (SPW-PRADORT), Pôle Enfants CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse) |
| المصدر: | https://hal.science/hal-03815545Test ; 2022. |
| بيانات النشر: | HAL CCSD |
| سنة النشر: | 2022 |
| المجموعة: | Université Toulouse III - Paul Sabatier: HAL-UPS |
| مصطلحات موضوعية: | addiction, Prader-Willi syndrome, eating behavior, amygdala, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology |
| الوصف: | Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental disorder involving nutritional, endocrine /metabolic, emotional and behavior dimensions. There is evidence for impaired hypothalamic development and function in PWS, involving oxytocin and ghrelin, which can account for the typical PWS phenotype. Hyperphagia with addiction-like behavior is one of the common features of PWS and is a consequence of the hypothalamic dysfunction. In this study, we hypothesized that brain regions associated with compulsive eating behavior would be abnormally activated by food-related odors in PWS, as these can stimulate the appetite and induce hunger-related behavior. |
| نوع الوثيقة: | report |
| اللغة: | English |
| العلاقة: | hal-03815545; https://hal.science/hal-03815545Test; https://hal.science/hal-03815545/documentTest; https://hal.science/hal-03815545/file/2022.08.03.22278273v1.full.pdfTest |
| DOI: | 10.1101/2022.08.03.22278273 |
| الإتاحة: | https://doi.org/10.1101/2022.08.03.22278273Test https://hal.science/hal-03815545Test https://hal.science/hal-03815545/documentTest https://hal.science/hal-03815545/file/2022.08.03.22278273v1.full.pdfTest |
| حقوق: | http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.AF9A2DAE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1101/2022.08.03.22278273 |
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