دورية أكاديمية
Prevalence of, and risk factors for, dental sequelae in adolescents who underwent cancer therapy during childhood
| العنوان: | Prevalence of, and risk factors for, dental sequelae in adolescents who underwent cancer therapy during childhood |
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| المؤلفون: | Rabassa Blanco, Judit, Brunet i Llobet, Lluís, Marcote-Sinclair, Paula, Balsells-Mejía, Sol, Correa-Llano, María Genoveva, Miranda i Rius, Jaume |
| المصدر: | Articles publicats en revistes (Odontoestomatologia) |
| بيانات النشر: | John Wiley & Sons |
| سنة النشر: | 2022 |
| المجموعة: | Dipòsit Digital de la Universitat de Barcelona |
| مصطلحات موضوعية: | Quimioteràpia del càncer, Càncer en els infants, Efectes secundaris, Malformacions dentals, Higiene bucal, Cancer chemotherapy, Cancer in children, Side effects, Dental abnormalities, Oral hygiene |
| الوصف: | Introduction: The increase in survival rates in children treated for cancer has been accompanied by a rise in sequelae in permanent teeth. The aim of the study was to correlate the type of cancer therapy administered to patients during early childhood and the dental sequelae recorded in survivors. Material and methods: Single-center retrospective cohort study carried out at the Children's University Hospital of Sant Joan de Déu in Barcelona, Spain. Hundred and nine patients who had received cancer treatment during early childhood were randomly examined and grouped according to diagnosis and cancer therapy received. The type of therapy was correlated with the number and severity of dental lesions that patients presented in adolescence. Results: Dental sequelae of some kind were present in 85.3% of patients. Microdontia was the most prevalent (52.3%). Treatment with alkylating agents had a relative risk of presenting moderate lesions of 3.36 (1.18-9.60), and one of 2.29 (1.07-4.91) of presenting severe lesions. Topoisomerase inhibitors and cytotoxic antibiotics presented relative risks of 1.6 (1.07-2.38) and 2.08 (1.02-4.26) of root alterations and agenesis, respectively. Conclusions: Treatment with alkylating agents together with cytotoxic antibiotics and topoisomerase inhibitors was associated with a higher relative risk of microdontia, agenesis, and root shortening. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 11 p.; application/pdf |
| اللغة: | English |
| تدمد: | 1354-523X |
| العلاقة: | Reproducció del document publicat a: https://doi.org/10.1111/odi.14317Test; Oral Diseases, 2022, vol. 16, num. 7; https://doi.org/10.1111/odi.14317Test; http://hdl.handle.net/2445/197040Test; 728595 |
| الإتاحة: | https://doi.org/10.1111/odi.14317Test http://hdl.handle.net/2445/197040Test |
| حقوق: | cc by (c) Rabassa Blanco, Judit et al., 2022 ; https://creativecommons.org/licenses/by/4.0Test/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.AF84B0B |
| قاعدة البيانات: | BASE |
| تدمد: | 1354523X |
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