التفاصيل البيبلوغرافية
العنوان: |
A win‐win platform: Stabilized black phosphorous nanosheets loading gallium ions for enhancing the healing of bacterial‐infected wounds through synergistic antibacterial approaches |
المؤلفون: |
Li, Zhiwei, Ren, Jiwei, Sui, Xin, Yang, Nan, Li, Sijia, Qi, Le, Li, Sining, Fan, Yixin, Liu, Zhihui |
المساهمون: |
Department of Finance of Jilin Province, Department of Science and Technology of Jilin Province |
المصدر: |
International Wound Journal ; volume 21, issue 6 ; ISSN 1742-4801 1742-481X |
بيانات النشر: |
Wiley |
سنة النشر: |
2024 |
المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
الوصف: |
Bacterial infection is the most common complication in wound healing, highlighting an urgent need for the development of innovative antibacterial technologies and treatments to address the growing threats posed by bacterial infections. Black phosphorus nanosheets (BPNSs), as a promising two‐dimensional nanomaterial, have been utilized in treating infected wounds. However, BP's limited stability restricts its application. In this study, we enhance BP's stability and its antibacterial properties by anchoring gallium ions (Ga 3+ ) onto BP's surface, creating a novel antibacterial platform. This modification reduces BP's electron density and enhances its antibacterial capabilities through a synergistic effect. Under near‐infrared (NIR) irradiation, the BP/Ga 3+ combination exerts antibacterial effects via photothermal therapy (PTT) and photodynamic therapy (PDT), while also releasing Ga 3+ . The Ga 3+ employ a ‘Trojan horse strategy’ to disrupt iron metabolism, significantly boosting the antibacterial efficacy of the complex. This innovative material offers a viable alternative to antibiotics and holds significant promise for treating infected wounds and aiding skin reconstruction. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1111/iwj.14940 |
الإتاحة: |
https://doi.org/10.1111/iwj.14940Test |
حقوق: |
http://creativecommons.org/licenses/by-nc/4.0Test/ |
رقم الانضمام: |
edsbas.ADE26571 |
قاعدة البيانات: |
BASE |