مؤتمر
How many women can benefit from a full intrapartum antibiotic prphylaxis for prevention of perinatal group B streptococcal disease?
| العنوان: | How many women can benefit from a full intrapartum antibiotic prphylaxis for prevention of perinatal group B streptococcal disease? |
|---|---|
| المؤلفون: | MELIN, Pierrette, Lorquet, Sophie, Rodriguez Cuns, Grisel, Foidart, Jean-Michel, De Mol, Patrick |
| المساهمون: | Centre National de Référence des Streptocoques du Groupe B |
| المصدر: | Program and Abstracts of the 44th Intersciences Conference on Antimicrobial Agents and Chemotherapy, Abstract du poster G-499 (2004-11); 44th Intersciences Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Washington, United States [US], du 30 octobre au 2 novembre 2004 |
| بيانات النشر: | American Society for Microbiology (ASM) |
| سنة النشر: | 2004 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | Group B streptococci, perinatal infections, intrapartum antibiotic prophylaxis, pregnant women, Human health sciences, Reproductive medicine (gynecology, andrology, obstetrics), Immunology & infectious disease, Sciences de la santé humaine, Médecine de la reproduction (Gynécologie, andrologie, obstétrique), Immunologie & maladie infectieuse |
| الوصف: | peer reviewed ; Background: In Belgium as in many Western countries, GBS are still the leading cause of severe perinatal infections. Current guidelines for prevention recommend intrapartum antimicrobial prohylaxis (IAP) administered promptly before delivery to pregnant women colonized with GBS. The risk of vertical GBS transmission to the newborn decreases as the duration of prophylaxis increases. The considered threshold for prophylaxis adequacy is the first dose administered at least 4 hours before delivery. Objective: To evaluate the proportion of pregnant women who could benefit from an adequate IAP for the prevention of GBS perinatal infections. Methods: Between June and October 2003, we recorded in two hospitals the elapse time between admission for labor and delivery. We assumed 5 hours represent a useful threshold to allow admission, revision of chart and administration of adequate IAP. The status of vaginal colonization with GBS was determined by CDC’s recommended culture method with Granada agar added. Results: Among 532 women, 27.3 % delivered within 5 hours after admission for labor. The colonization rate for GBS was 25.6 %. The distribution of elapse time between admission and delivery for GBS colonized pregnant women was not significantly different from non colonized women (p <= 1). Conclusions: 1) With the current prevention strategy, 27.3 % of these pregnant women would not have benefit from adequate prophylaxis 2) These results highlight the importance of an efficient organization to warranty prompt administration of IAP as soon as possible when mandatory. 3) If a rapid intrapartum screening test is used, no delay can be afforded “from ward to bench to bed”. |
| نوع الوثيقة: | conference object report |
| اللغة: | English |
| العلاقة: | https://orbi.uliege.be/handle/2268/68515Test; info:hdl:2268/68515; https://orbi.uliege.be/bitstream/2268/68515/1/Time%20to%20delivery%20ICAAC%202004.pdfTest |
| الإتاحة: | https://orbi.uliege.be/handle/2268/68515Test https://orbi.uliege.be/bitstream/2268/68515/1/Time%20to%20delivery%20ICAAC%202004.pdfTest |
| حقوق: | open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.AD10559C |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |