دورية أكاديمية
أعرض في EDS

Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa.

التفاصيل البيبلوغرافية
العنوان: Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa.
المؤلفون: Delanaye, Pierre, Vidal-Petiot, Emmanuelle, Björk, Jonas, Ebert, Natalie, Eriksen, Björn O, Dubourg, Laurence, Grubb, Anders, Hansson, Magnus, Littmann, Karin, Mariat, Christophe, Melsom, Toralf, Schaeffner, Elke, Sundin, Per-Ola, Bökenkamp, Arend, Berg, Ulla B, Åsling-Monemi, Kajsa, Åkesson, Anna, Larsson, Anders, Cavalier, Etienne, Dalton, R Neil, Courbebaisse, Marie, Couzi, Lionel, Gaillard, Francois, Garrouste, Cyril, Jacquemont, Lola, Kamar, Nassim, Legendre, Christophe, Rostaing, Lionel, Stehlé, Thomas, Haymann, Jean-Philippe, Selistre, Luciano da Silva, Strogoff-de-Matos, Jorge P, Bukabau, Justine B, Sumaili, Ernest K, Yayo, Eric, Monnet, Dagui, Nyman, Ulf, Pottel, Hans, Flamant, Martin
المصدر: Nephrology Dialysis Transplantation, 38 (1), 106 - 118 (2023-01-23)
بيانات النشر: Oxford University Press (OUP)
سنة النشر: 2023
المجموعة: University of Liège: ORBi (Open Repository and Bibliography)
مصطلحات موضوعية: creatinine, glomerular filtration rate, race, Transplantation, Nephrology, Human health sciences, Urology & nephrology, Laboratory medicine & medical technology, Sciences de la santé humaine, Urologie & néphrologie, Médecine de laboratoire & technologie médicale
الوصف: peer reviewed ; ("[en] BACKGROUND: A new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts. METHODS: Standardized creatinine and measured glomerular filtration rate (GFR) from the European EKFC cohorts (n = 13 856 including 6031 individuals in the external validation cohort), from France (n = 4429, including 964 Black Europeans), from Brazil (n = 100) and from Africa (n = 508) were used to test the performances of the equations. A matched analysis between White Europeans and Black Africans or Black Europeans was performed. RESULTS: In White Europeans (n = 9496), both the EKFC and LMREV equations outperformed CKD-EPIAS (bias of -0.6 and -3.2, respectively versus 5.0 mL/min/1.73 m², and accuracy within 30% of 86.9 and 87.4, respectively, versus 80.9%). In Black Europeans and Black Africans, the best performance was observed with the EKFC equation using a specific Q-value (= concentration of serum creatinine in healthy males and females). These results were confirmed in matched analyses, which showed that serum creatinine concentrations were different in White Europeans, Black Europeans and Black Africans for the same measured GFR, age, sex and body mass index. Creatinine differences were more relevant in males. CONCLUSION: In a European and African cohort, the performances of CKD-EPIAS remain suboptimal. The EKFC equation, using usual or dedicated population-specific Q-values, presents the best performance in the whole age range in the European and African populations included in this study.","[en] ","")
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0931-0509
1460-2385
العلاقة: urn:issn:0931-0509; urn:issn:1460-2385; https://orbi.uliege.be/handle/2268/300146Test; info:hdl:2268/300146; https://orbi.uliege.be/bitstream/2268/300146/1/DelanayeNDT2023.pdfTest; scopus-id:2-s2.0-85141209736; info:pmid:36002032
DOI: 10.1093/ndt/gfac241
الإتاحة: https://doi.org/10.1093/ndt/gfac241Test
https://orbi.uliege.be/handle/2268/300146Test
https://orbi.uliege.be/bitstream/2268/300146/1/DelanayeNDT2023.pdfTest
حقوق: open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.AAD4AE2F
قاعدة البيانات: BASE
الوصف
تدمد:09310509
14602385
DOI:10.1093/ndt/gfac241