دورية أكاديمية
Primary Adrenal Insufficiency in Autoimmune Polyglandular Syndrome Type 1 - A Case Report and Literature Review
| العنوان: | Primary Adrenal Insufficiency in Autoimmune Polyglandular Syndrome Type 1 - A Case Report and Literature Review |
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| المؤلفون: | Qadeer, Hafiza A, MD, Samkutty, Reshma, Moss, Caitlyn |
| المصدر: | Advances in Clinical Medical Research and Healthcare Delivery |
| بيانات النشر: | RocScholar |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | APS type 1, hypoparathyroidism, primary adrenal insufficiency, Addison's disease, hypocalcemia, Endocrine System Diseases |
| الوصف: | Autoimmune Polyglandular Syndrome (APS) type 1 is a rare autosomal recessive disorder secondary to AIRE gene mutation, that is classically characterized by autoimmune hypoparathyroidism, chronic mucocutaneous candidiasis and Addison’s disease. A review of the literature shows that these disease manifestations may present in any order in different age groups. Patients with APS type 1 are also at risk for other endocrinopathies. We present the case of a female patient with a history of APS type 1 and type 1 diabetes who presented with new onset hypoglycemia and decreased insulin requirement and was diagnosed with new onset adrenal insufficiency due to Addison’s disease. One challenge we experienced in this patient diagnosed with concomitant autoimmune hypoparathyroidism and adrenal insufficiency was regulation of serum calcium, as cortisol replacement therapy contributes to urinary calcium loss. The goal calcium level is thus maintained at the lower limit of normal. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://scholar.rochesterregional.org/advances/vol4/iss1/6Test; https://scholar.rochesterregional.org/context/advances/article/1196/viewcontent/ACMRHD1196_proof.pdfTest |
| DOI: | 10.53785/2769-2779.1196 |
| الإتاحة: | https://doi.org/10.53785/2769-2779.1196Test https://scholar.rochesterregional.org/advances/vol4/iss1/6Test https://scholar.rochesterregional.org/context/advances/article/1196/viewcontent/ACMRHD1196_proof.pdfTest |
| حقوق: | http://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: | edsbas.AA40DABD |
| قاعدة البيانات: | BASE |
| DOI: | 10.53785/2769-2779.1196 |
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