دورية أكاديمية
The Effect of Physical Exercise on Oxidation Capacity and Utero-Placental Circulation in Pregnancies with Gestational Diabetes Mellitus and Uncomplicated Pregnancies, a Pilot Study
| العنوان: | The Effect of Physical Exercise on Oxidation Capacity and Utero-Placental Circulation in Pregnancies with Gestational Diabetes Mellitus and Uncomplicated Pregnancies, a Pilot Study |
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| المؤلفون: | Chatzakis C., Sotiriadis A., Fatouros I.G., Jamurtas A.Z., Deli C.K., Papagianni M., Dinas K., Mastorakos G. |
| المصدر: | Diagnostics ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137379129&doi=10.3390%2fdiagnostics12071732&partnerID=40&md5=1769c0409f247a11d87742ec92149e7aTest |
| سنة النشر: | 2022 |
| المجموعة: | University of Thessaly Institutional Repository / Ιδρυματικό Αποθετήριο Πανεπιστημίου Θεσσαλίας |
| مصطلحات موضوعية: | catalase, glutathione, adult, aerobic exercise, Article, body mass, body weight gain, clinical article, controlled study, cross-sectional study, female, follow up, gestational age, human, maternal age, moderate intensity exercise, oral glucose tolerance test, oxidation, parity, pilot study, placenta circulation, pregnancy, pregnancy diabetes mellitus, pregnant woman, pulsatility index, third trimester pregnancy, total antioxidant capacity, umbilical artery, uterine artery, MDPI |
| الوصف: | Background: Gestational diabetes mellitus (GDM) is associated with aggravated oxidation capacity and utero-placental circulation, while aerobic exercise could improve both. The study aims to assess oxidation capacity and utero-placental circulation before and after a bout of aerobic exercise in GDM and uncomplicated pregnancies.; Methods: In this cross-sectional study, women with GDM (GDMs) and women with uncomplicated pregnancies(controls), underwent 30 min of moderate intensity cycling. Total antioxidant capacity (TAC), catalase activity (CAT), reduced glutathione (GSH), Uterine Arteries (UtA PI) and Umbilical Artery (UmA PI) pulsatility indexes were estimated prior-to, immediately after and one hour after exercise; Results: In each group, 25 pregnant women were included. In both groups, between prior-to and immediately after exercise, TAC and CAT increased, while GSH decreased, (p < 0.001). In GDMs, CAT was lower than controls at any time point (p < 0.05), while in GDMs delta(Δ) CAT (prior-to and immediately after exercise) was lower than controls (p = 0.003). In GDMs, UtA PI centiles decreased between prior-to and either immediately or one hour after exercise, while they did not change in controls. In GDMs, pre-conceptional BMI and weight gain predicted negatively ΔTAC (prior-to to one hour after exercise); Conclusions: Moderate intensity exercise bout improves oxidation capacity in GDM and uncomplicated pregnancies, although at a lesser extent in the former. Exercise leads to decreased UtA arteries resistance in women with GDM. © 2022 by the authors. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 20754418 |
| العلاقة: | http://hdl.handle.net/11615/72579Test |
| DOI: | 10.3390/diagnostics12071732 |
| الإتاحة: | https://doi.org/10.3390/diagnostics12071732Test http://hdl.handle.net/11615/72579Test |
| رقم الانضمام: | edsbas.A9678644 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20754418 |
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| DOI: | 10.3390/diagnostics12071732 |