دورية أكاديمية

Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection.

التفاصيل البيبلوغرافية
العنوان: Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection.
المؤلفون: Zindovic, Igor, Gudbjartsson, Tomas, Ahlsson, Anders, Fuglsang, Simon, Gunn, Jarmo, Hansson, Emma C, Hjortdal, Vibeke, Järvelä, Kati, Jeppsson, Anders, Mennander, Ari, Olsson, Christian, Pan, Emily, Sjögren, Johan, Wickbom, Anders, Geirsson, Arnar, Nozohoor, Shahab
المساهمون: 1 Department of Clinical Sciences and Department of Cardiothoracic Surgery, Lund University, Skane University Hospital, Lund, Sweden. Electronic address: igor.zindovic@med.lu.se. 2 Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 3 Department of Cardiothoracic and Vascular Surgery, Orebro University Hospital and School of Health and Medicine, Orebro University, Orebro, Sweden. 4 Department of Thoracic and Cardiovascular Surgery, Aarhus University Hospital, Skejby, Denmark. 5 Heart Center, Turku University Hospital and University of Turku, Turku, Finland. 6 Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. 7 Heart Center, Tampere University Hospital, Tampere, Finland. 8 Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden. 9 Department of Clinical Sciences and Department of Cardiothoracic Surgery, Lund University, Skane University Hospital, Lund, Sweden. 10 Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, Section of Cardiac Surgery, Yale University School of Medicine, New Haven, Conn.
المصدر: The Journal of thoracic and cardiovascular surgery
بيانات النشر: Mosby-Elsevier
سنة النشر: 2019
المجموعة: Hirsla - Landspítali University Hospital research archive
مصطلحات موضوعية: aorta, dissection, malperfusion, Slagæðargúlpur, Skurðlækningar, Postoperative Complications, Aneurysm, Dissecting
الوصف: To access publisher's full text version of this article click on the hyperlink below ; To evaluate the effect of preoperative malperfusion on 30-day and late mortality and postoperative complications using data from the Nordic Consortium for Acute Type A Aortic Dissection (ATAAD) registry. We studied 1159 patients who underwent ATAAD surgery between January 2005 and December 2014 at 8 Nordic centers. Multivariable logistic and Cox regression analyses were performed to identify independent predictors of 30-day and late mortality. Preoperative malperfusion was identified in 381 of 1159 patients (33%) who underwent ATAAD surgery. Thirty-day mortality was 28.9% in patients with preoperative malperfusion and 12.1% in those without. Independent predictors of 30-day mortality included any malperfusion (odds ratio, 2.76; 95% confidence interval [CI], 1.94-3.93), cardiac malperfusion (odds ratio, 2.37; 95% CI, 1.34-4.17), renal malperfusion (odds ratio, 2.38; 95% CI, 1.23-4.61) and peripheral malperfusion (odds ratio, 1.95; 95% CI, 1.26-3.01). Any malperfusion (hazard ratio, 1.72; 95% CI, 1.21-2.43), cardiac malperfusion (hazard ratio, 1.89; 95% CI, 1.24-2.87) and gastrointestinal malperfusion (hazard ratio, 2.25; 95% CI, 1.18-4.26) were predictors of late mortality. Malperfusion was associated with significantly poorer survival at 1, 3, and 5 years (95.0% ± 0.9% vs 88.7% ± 1.9%, 90.1% ± 1.3% vs 84.0% ± 2.4%, and 85.4% ± 1.7% vs 80.8% ± 2.7%; log rank P = .009). Malperfusion has a significant influence on early and late outcomes in ATAAD surgery. Management of preoperative malperfusion remains a major challenge in reducing mortality associated with surgical treatment of ATAAD. ; University of Iceland Research Fund Landspitali Research Fund Mats Kleberg Foundation
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1097-685X
العلاقة: https://www.sciencedirect.com/science/article/pii/S0022522318329283Test; Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection. 2019,157(4):1324-1333 J Thorac Cardiovasc Surg; http://hdl.handle.net/2336/620917Test; Journal of thoracic and cardiovascular surgery
DOI: 10.1016/j.jtcvs.2018.10.134
الإتاحة: https://doi.org/10.1016/j.jtcvs.2018.10.134Test
http://hdl.handle.net/2336/620917Test
حقوق: National Consortium - Landsaðgangur
رقم الانضمام: edsbas.A9412633
قاعدة البيانات: BASE
الوصف
تدمد:1097685X
DOI:10.1016/j.jtcvs.2018.10.134