دورية أكاديمية
Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection.
العنوان: | Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection. |
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المؤلفون: | Zindovic, Igor, Gudbjartsson, Tomas, Ahlsson, Anders, Fuglsang, Simon, Gunn, Jarmo, Hansson, Emma C, Hjortdal, Vibeke, Järvelä, Kati, Jeppsson, Anders, Mennander, Ari, Olsson, Christian, Pan, Emily, Sjögren, Johan, Wickbom, Anders, Geirsson, Arnar, Nozohoor, Shahab |
المساهمون: | 1 Department of Clinical Sciences and Department of Cardiothoracic Surgery, Lund University, Skane University Hospital, Lund, Sweden. Electronic address: igor.zindovic@med.lu.se. 2 Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 3 Department of Cardiothoracic and Vascular Surgery, Orebro University Hospital and School of Health and Medicine, Orebro University, Orebro, Sweden. 4 Department of Thoracic and Cardiovascular Surgery, Aarhus University Hospital, Skejby, Denmark. 5 Heart Center, Turku University Hospital and University of Turku, Turku, Finland. 6 Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. 7 Heart Center, Tampere University Hospital, Tampere, Finland. 8 Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden. 9 Department of Clinical Sciences and Department of Cardiothoracic Surgery, Lund University, Skane University Hospital, Lund, Sweden. 10 Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, Section of Cardiac Surgery, Yale University School of Medicine, New Haven, Conn. |
المصدر: | The Journal of thoracic and cardiovascular surgery |
بيانات النشر: | Mosby-Elsevier |
سنة النشر: | 2019 |
المجموعة: | Hirsla - Landspítali University Hospital research archive |
مصطلحات موضوعية: | aorta, dissection, malperfusion, Slagæðargúlpur, Skurðlækningar, Postoperative Complications, Aneurysm, Dissecting |
الوصف: | To access publisher's full text version of this article click on the hyperlink below ; To evaluate the effect of preoperative malperfusion on 30-day and late mortality and postoperative complications using data from the Nordic Consortium for Acute Type A Aortic Dissection (ATAAD) registry. We studied 1159 patients who underwent ATAAD surgery between January 2005 and December 2014 at 8 Nordic centers. Multivariable logistic and Cox regression analyses were performed to identify independent predictors of 30-day and late mortality. Preoperative malperfusion was identified in 381 of 1159 patients (33%) who underwent ATAAD surgery. Thirty-day mortality was 28.9% in patients with preoperative malperfusion and 12.1% in those without. Independent predictors of 30-day mortality included any malperfusion (odds ratio, 2.76; 95% confidence interval [CI], 1.94-3.93), cardiac malperfusion (odds ratio, 2.37; 95% CI, 1.34-4.17), renal malperfusion (odds ratio, 2.38; 95% CI, 1.23-4.61) and peripheral malperfusion (odds ratio, 1.95; 95% CI, 1.26-3.01). Any malperfusion (hazard ratio, 1.72; 95% CI, 1.21-2.43), cardiac malperfusion (hazard ratio, 1.89; 95% CI, 1.24-2.87) and gastrointestinal malperfusion (hazard ratio, 2.25; 95% CI, 1.18-4.26) were predictors of late mortality. Malperfusion was associated with significantly poorer survival at 1, 3, and 5 years (95.0% ± 0.9% vs 88.7% ± 1.9%, 90.1% ± 1.3% vs 84.0% ± 2.4%, and 85.4% ± 1.7% vs 80.8% ± 2.7%; log rank P = .009). Malperfusion has a significant influence on early and late outcomes in ATAAD surgery. Management of preoperative malperfusion remains a major challenge in reducing mortality associated with surgical treatment of ATAAD. ; University of Iceland Research Fund Landspitali Research Fund Mats Kleberg Foundation |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1097-685X |
العلاقة: | https://www.sciencedirect.com/science/article/pii/S0022522318329283Test; Malperfusion in acute type A aortic dissection: An update from the Nordic Consortium for Acute Type A Aortic Dissection. 2019,157(4):1324-1333 J Thorac Cardiovasc Surg; http://hdl.handle.net/2336/620917Test; Journal of thoracic and cardiovascular surgery |
DOI: | 10.1016/j.jtcvs.2018.10.134 |
الإتاحة: | https://doi.org/10.1016/j.jtcvs.2018.10.134Test http://hdl.handle.net/2336/620917Test |
حقوق: | National Consortium - Landsaðgangur |
رقم الانضمام: | edsbas.A9412633 |
قاعدة البيانات: | BASE |
تدمد: | 1097685X |
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DOI: | 10.1016/j.jtcvs.2018.10.134 |