التفاصيل البيبلوغرافية
| العنوان: |
SEOM-GECP-GETTHI Clinical Guidelines for the treatment of patients with thymic epithelial tumours (2021) |
| المؤلفون: |
Remón, Jordi, Bernabé-Caro, Reyes, Felip, E., González Larriba, J.L., Lázaro, M., Mielgo Rubio, X, Sánchez, A., Sullivan, I., Massuti, B. |
| المساهمون: |
Universidad de Sevilla. Departamento de Medicina |
| بيانات النشر: |
SPRINGER |
| سنة النشر: |
2022 |
| المجموعة: |
idUS - Deposito de Investigación Universidad de Sevilla |
| مصطلحات موضوعية: |
Thymic epithelial tumours, Chemotherapy, Lenvatinib, Nivolumab, Multidisciplinary |
| الوصف: |
Thymic epithelial tumours (TET) represent a heterogeneous group of rare malignancies that include thymomas and thymic carcinoma. Treatment of TET is based on the resectability of the tumour. If this is considered achievable upfront, surgical resection is the cornerstone of treatment. Platinum-based chemotherapy is the standard regimen for advanced TET. Due to the rarity of this disease, treatment decisions should be discussed in specifc multidisciplinary tumour boards, and there are few prospective clinical studies with new strategies. However, several pathways involved in TET have been explored as potential targets for new therapies in previously treated patients, such as multi-tyrosine kinase inhibitors with antiangiogenic properties and immune checkpoint inhibitors (ICI). One third of patient with thymoma present an autoimmune disorders, increasing the risk of immune-related adverse events and autoimmune fares under ICIs. In these guidelines, we summarize the current evidence for the therapeutic approach in patients with TET and defne levels of evidence for these decisions |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
Cinical and Translational Oncology, 24 (4), 635-645.; https://link.springer.com/article/10.1007/s12094-022-02788-wTest; https://idus.us.es/handle//11441/137563Test |
| الإتاحة: |
https://idus.us.es/handle//11441/137563Test |
| حقوق: |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.A8AC93D0 |
| قاعدة البيانات: |
BASE |
