دورية أكاديمية
Can sodium-glucose cotransporter 2 inhibitors be beneficial in patients with acute myocardial infarction?
| العنوان: | Can sodium-glucose cotransporter 2 inhibitors be beneficial in patients with acute myocardial infarction? |
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| المؤلفون: | von Lewinski, Dirk, Benedikt, Martin, Tripolt, Norbert, Wallner, Markus, Sourij, Harald, Kolesnik, Ewald |
| المصدر: | Kardiologia Polska; Vol 79, No 5 (2021); 503-509 ; Kardiologia Polska (Polish Heart Journal); Vol 79, No 5 (2021); 503-509 |
| بيانات النشر: | Polish Cardiac Society |
| سنة النشر: | 2021 |
| المجموعة: | Via Medica Journals |
| مصطلحات موضوعية: | sodium-glucose cotransporter 2 inhibitors, myocardial infarction, metabolism, clinical trials |
| الوصف: | The sodium-glucose cotransporter 2 inhibitors (SGLT2i), empagliflozin, dapagliflozin, and canagliflozin, have shown impressive beneficial effects in patients with type 2 diabetes mellitus in mandatory cardiovascular outcome trials. Retrospective data analysis revealed signals that pointed towards positive effects independent of the antidiabetic effects. This could be confirmed for empagliflozin and dapagliflozin in chronic heart failure with reduced ejection fraction alone, where rates of hospitalization for heart failure and cumulative major adverse cardiovascular events were reduced to a similar extent in patients with and without diabetes mellitus as in corresponding outcome trials. Cardiac remodeling following myocardial infarction leads to heart failure with reduced ejection fraction in many patients and aggravates morbidity and mortality. Clinical data of SGLT2i treatment after acute myocardial infarction is sparse. This review focuses on available experimental data on the effects of SGLT2i used before, during, and after myocardial infarction as well as already published and currently ongoing clinical trials. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://journals.viamedica.pl/kardiologia_polska/article/view/KP.15969Test |
| DOI: | 10.33963/KP.15969 |
| الإتاحة: | https://doi.org/10.33963/KP.15969Test https://journals.viamedica.pl/kardiologia_polska/article/view/KP.15969Test |
| حقوق: | The copyright to the submitted manuscript is held my the Author, who grants the Polish Cardiac Society a nonexclusive licence to use, reproduce, and distribute the work, including for commercial purposes. Kardiol Pol in an open access journal applying the Creative Commonst Attribution-Non Commercial-No Derivates 4.0 International Licence (CC BY-NC-ND 4.0), allowing third parties to download articles and share them with others, provided the original work is properly cited, not changed in any way, distributed under the same licence, and used for noncommercial purposes only. For commercial use, please contact the journal office: kardiologiapolska@ptkardio.pl. ; Przesyłając manuskrypt wraz z ilustracjami i tabelami, automatycznie i nieodpłatnie przenosi (przenoszą) na Polskie Towarzystwo Kardiologiczne wszelkie prawa autorskie do wydawania oraz rozpowszechniania nadesłanych materiałów we wszystkich znanych formach i na wszystkich znanych polach eksploatacji, bez ograniczeń terytorialnych językowych pod warunkiem, że materiały te zostaną zaakceptowane do publikacji. |
| رقم الانضمام: | edsbas.A84BA832 |
| قاعدة البيانات: | BASE |
| DOI: | 10.33963/KP.15969 |
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