كتاب
Stimuli-responsive Nanocomposite Hydrogels Incorporating Soft Nanoparticles for Biomedical Applications
| العنوان: | Stimuli-responsive Nanocomposite Hydrogels Incorporating Soft Nanoparticles for Biomedical Applications |
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| المؤلفون: | Lavrador, P., Borges, J., Gaspar, V. M., Mano, J. F. |
| بيانات النشر: | Royal Society of Chemistry |
| سنة النشر: | 2024 |
| المجموعة: | Repositório Institucional da Universidade de Aveiro (RIA) |
| الوصف: | Soft nanoparticles represent a unique class of nanomaterials that can be engineered to react and adapt distinctly in different biological milieus while modulating the presentation of biochemical and biophysical cues to neighbouring receptive cells. This flexibility has fuelled the development of soft nanoparticle-laden nanocomposite hydrogels that are increasingly sophisticated in stimuli-responsiveness and promising for satisfying a plethora of biomedical applications. Such hybrid platforms can be encoded with intelligent disease-discerning tools, smart adaptability under external triggers for bioactive cargo delivery or be engineered for manipulating biomechanical properties in different tissue microenvironments. In addition, they can be interfaced with biological components(i.e. enzymes, cell membranes) or specific substrates recognisable by biological machinery, yielding biomolecule-responsive systems that perceive changes in their surroundings and alter their therapeutic outputs accordingly. In essence, this chapter highlights the unique opportunities of soft nanoparticles to function as versatile building blocks for programming and modulating a large array of features in hydrogel-based platforms, thus extending their biofunctionality and applicability in tissue engineering and regenerative medicine practices. ; published |
| نوع الوثيقة: | book part |
| اللغة: | English |
| ردمك: | 978-1-78801-757-2 978-1-83916-112-4 1-78801-757-9 1-83916-112-4 |
| العلاقة: | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FQUI-OUT%2F30658%2F2017/PT; info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBTM-MAT%2F31498%2F2017/PT; info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBTM-SAL%2F30503%2F2017/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50011%2F2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PT; info:eu-repo/grantAgreement/FCT/CEEC IND 2017/CEECIND%2F03202%2F2017%2FCP1459%2FCT0042/PT; info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F141834%2F2018/PT; http://hdl.handle.net/10773/34186Test |
| DOI: | 10.1039/9781839161124-00566 |
| الإتاحة: | https://doi.org/10.1039/9781839161124-00566Test http://hdl.handle.net/10773/34186Test |
| حقوق: | embargoedAccess ; https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.A74B445E |
| قاعدة البيانات: | BASE |
| ردمك: | 9781788017572 9781839161124 1788017579 1839161124 |
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| DOI: | 10.1039/9781839161124-00566 |