دورية أكاديمية
Efficacy and Safety of the Medium Cut-Off Elisio HX Dialyzer
| العنوان: | Efficacy and Safety of the Medium Cut-Off Elisio HX Dialyzer |
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| المؤلفون: | Maduell, Francisco, Broseta, José Jesús, Rodríguez-Espinosa, Diana, Del Risco-Zevallos, Jimena, Gómez, Miquel, Rodas, Lida M., Arias-Guillén, Marta, Vera, Manel, Fontseré, Néstor, Salgado, Maria del Carmen, Rico, Nayra |
| المصدر: | Blood Purification ; volume 52, issue 1, page 68-74 ; ISSN 0253-5068 1421-9735 |
| بيانات النشر: | S. Karger AG |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Nephrology, Hematology, General Medicine |
| الوصف: | Introduction: The medium cut-off Elisio HX dialyzer by Nipro became commercially available in Europe in 2021, but there are still no reports of in vivo data. This study aimed to evaluate the safety and efficacy of it compared with previously evaluated hemodialysis (HD), expanded HD (HDx), and postdilution hemodiafiltration (HDF) treatments. Methods: A prospective study was carried out on 18 patients who underwent 5 dialysis sessions: FX80 Cordiax in HD, Elisio H19 in HD, Elisio HX19 in HDx, Theranova 400 in HDx, and FX80 Cordiax in HDF. The reduction ratios of urea, creatinine, ß2-microglobulin, myoglobin, kappa FLC, prolactin, α1-microglobulin, α1-acid glycoprotein, lambda FLC, and albumin were compared. Dialysate albumin loss was measured. Results: The comparison between the different dialysis modalities revealed no difference for small molecules, but HDx and HDF were significantly more efficient than HD for medium and large molecule removal. The efficacy of Elisio HX19 dialyzer in HDx was similar to the Theranova 400, superior to both dialyzers in HD, and slightly lower than HDF. Albumin losses in dialysate with HD dialyzers were less than 1 g, but between 1.5 and 2.5 g in HDx and HDF. The global removal score (GRS) values with HDx treatments were statistically significantly higher than those with HD. The highest GRS was obtained with the helixone dialyzer in HDF. Conclusions: The new MCO dialyzer, Elisio HX, performs with excellent behavior and tolerance. It represents an upgrade compared to their predecessor and is very close to the removal capacity of HDF treatment. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1159/000524644 |
| الإتاحة: | https://doi.org/10.1159/000524644Test https://karger.com/bpu/article-pdf/52/1/68/3961281/000524644.pdfTest |
| حقوق: | https://creativecommons.org/licenses/by-nc/4.0Test/ ; https://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: | edsbas.A3EC5146 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1159/000524644 |
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