دورية أكاديمية
Calf muscle density is independently associated with physical function in overweight and obese older adults
| العنوان: | Calf muscle density is independently associated with physical function in overweight and obese older adults |
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| المؤلفون: | Scott, D, Shore-Lorenti, C, McMillan, LB, Mesinovic, J, Clark, RA, Hayes, A, Sanders, KM, Duque, G, Ebeling, PR |
| بيانات النشر: | JMNI |
| سنة النشر: | 2018 |
| المجموعة: | The University of Melbourne: Digital Repository |
| الوصف: | OBJECTIVES: To determine whether associations of calf muscle density with physical function are independent of other determinants of functional decline in overweight and obese older adults. METHODS: This was a secondary analysis of a cross-sectional study of 85 community-dwelling overweight and obese adults (mean±SD age 62.8±7.9 years; BMI 32.3±6.1 kg/m2; 58% women). Peripheral quantitative computed tomography assessed mid-calf muscle density (66% tibial length) and dual-energy X-ray absorptiometry determined visceral fat area. Fasting glucose, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) and C-reactive protein (CRP) were analysed. Physical function assessments included hand grip and knee extension strength, balance path length (computerised posturography), stair climb test, Short Physical Performance Battery (SPPB) and self-reported falls efficacy (Modified Falls Efficacy Scale; M-FES). RESULTS: Visceral fat area, not muscle density, was independently associated with CRP and fasting glucose (B=0.025; 95% CI 0.009-0.042 and B=0.009; 0.001-0.017, respectively). Nevertheless, higher muscle density was independently associated with lower path length and stair climb time, and higher SPPB and M-FES scores (all P⟨0.05). Visceral fat area, fasting glucose and CRP did not mediate these associations. CONCLUSIONS: Higher calf muscle density predicts better physical function in overweight and obese older adults independent of insulin resistance, visceral adiposity or inflammation. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1108-7161 |
| العلاقة: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000427424400002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1cTest; Scott, D., Shore-Lorenti, C., McMillan, L. B., Mesinovic, J., Clark, R. A., Hayes, A., Sanders, K. M., Duque, G. & Ebeling, P. R. (2018). Calf muscle density is independently associated with physical function in overweight and obese older adults. JOURNAL OF MUSCULOSKELETAL & NEURONAL INTERACTIONS, 18 (1), pp.9-17; http://hdl.handle.net/11343/213157Test |
| الإتاحة: | http://hdl.handle.net/11343/213157Test http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000427424400002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1cTest |
| حقوق: | CC BY-NC-SA ; https://creativecommons.org/licenses/by-nc-sa/4.0Test |
| رقم الانضمام: | edsbas.A3648AC6 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 11087161 |
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