دورية أكاديمية

Cause of death during nasopharyngeal carcinoma survivorship: a population-based analysis

التفاصيل البيبلوغرافية
العنوان: Cause of death during nasopharyngeal carcinoma survivorship: a population-based analysis
المؤلفون: Zhou, Jie, Jiang, Zhenyu, Li, Yunhao, Shao, Xuwen, Liao, Haihong
المصدر: Frontiers in Oncology ; volume 13 ; ISSN 2234-943X
بيانات النشر: Frontiers Media SA
سنة النشر: 2023
المجموعة: Frontiers (Publisher - via CrossRef)
مصطلحات موضوعية: Cancer Research, Oncology
الوصف: Background Recently, the survival rate of nasopharyngeal carcinoma (NPC) patients has improved greatly due to developments in NPC treatments. But cause-specific mortality in NPC patients remains unclear. This study aims to investigate the common causes of death in NPC patients. Methods Eligible patients with NPC were included from the Surveillance, Epidemiology, and End Results (SEER) database. Standardized mortality ratios(SMRs) were calculated to compare death rates in NPC patients with those in the general population. Results A total of 3475 patients with NPC were included, of whom 1696 patients died during the follow-up period. 52.83% of deaths were caused by NPC, followed by other cancers (28.13%) and non-cancer causes (18.46%). The proportion of patients who died of NPC decreased over survival time. Moreover, non-cancer causes of death increase from 12.94% to 51.22% over time after 10 years of diagnosis. Heart diseases was the most common non-cancer cause of death in NPC patients. Conclusions Although NPC remains the leading cause of death after NPC diagnosis, other non-NPC causes of death represent an increased number of death in NPC patients. These findings support the involvement of multidisciplinary care for follow-up strategy in NPC patients.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
DOI: 10.3389/fonc.2023.1269118
DOI: 10.3389/fonc.2023.1269118/full
الإتاحة: https://doi.org/10.3389/fonc.2023.1269118Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.A28CC16B
قاعدة البيانات: BASE