دورية أكاديمية
Coping and Perception of Prognosis in Patients With Indolent Non-Hodgkin’s Lymphoma
العنوان: | Coping and Perception of Prognosis in Patients With Indolent Non-Hodgkin’s Lymphoma |
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المؤلفون: | Newcomb, Richard A, Johnson, P Connor, Yang, Daniel, Holmbeck, Katherine, Choe, Joanna, Nabily, Anisa, Lark, Porsha, Dhawale, Tejaswini, Amonoo, Hermioni L, El-Jawahri, Areej |
المساهمون: | National Cancer Institute |
المصدر: | The Oncologist ; volume 29, issue 5, page 441-449 ; ISSN 1083-7159 1549-490X |
بيانات النشر: | Oxford University Press (OUP) |
سنة النشر: | 2023 |
الوصف: | Background Indolent non-Hodgkin’s lymphomas (iNHL) are a heterogenous group of mostly incurable diseases with prolonged illness courses and prognostic uncertainty. Yet, studies evaluating coping and perception of prognosis are limited. Methods We conducted a cross-sectional study of adults newly diagnosed with iNHL in the past 3 months at a single academic center. We assessed quality of life (QOL: Functional Assessment of Cancer Therapy—General), psychological symptoms (Hospital Anxiety and Depression Scale), coping (Brief-COPE), and perception of prognosis (Prognosis Awareness Impact Scale). Results We enrolled 70.6% (48/68) of eligible patients. Patients had older age (mean = 66.9,sd = 10.5), were female (60.4%), predominantly identified as White (85.4%), and had at least received a college degree (75%). Chronic lymphocytic leukemia (39.6%) and follicular lymphoma (33.3%) were the most common diagnoses. Overall, 27.1% and 14.6% of patients reported clinically significant anxiety and PTSD symptoms, respectively. Patients highly utilized acceptance (56.2%), seeking emotional support (47.9%), and denial (47.9%) as coping strategies at diagnosis. While 66.7% of patients recalled their oncologist assessment of illness as incurable, only 35.4% reported that the illness is unlikely to be cured. Overall, 45.8% indicated that they were worried about prognosis and 31.2% reported perseverating on their prognosis. Higher emotional coping with prognosis was associated with fewer anxiety (B = −0.6, SE = 0.2, P < .001), depression (B = −0.3, SE = .1, P = .005), and PTSD (B = −1.3, SE = 0.4, P < .001) symptoms and better QOL (B = 1.7, SE = 0.4, P < .001). Discussion Patients with iNHL report substantial psychological distress, a diversity of coping strategies, and complex cognitive understanding of their prognosis. Interventions, which address prognostic uncertainty and promote positive emotional coping with prognosis, may ameliorate psychological distress in this population. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1093/oncolo/oyad295 |
الإتاحة: | https://doi.org/10.1093/oncolo/oyad295Test https://academic.oup.com/oncolo/article-pdf/29/5/441/57396326/oyad295.pdfTest |
حقوق: | https://creativecommons.org/licenses/by/4.0Test/ |
رقم الانضمام: | edsbas.A0F7B3BD |
قاعدة البيانات: | BASE |
DOI: | 10.1093/oncolo/oyad295 |
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