مراجعة
Effect of pre/postconditioning at temporary clipping
العنوان: | Effect of pre/postconditioning at temporary clipping |
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المساهمون: | Uludağ Üniversitesi/Tıp Fakültesi/Nöroşirürji Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı., orcid:0000-0001-5472-9065, Taşkapılıoğlu, Mevlüt Özgür, Morali, Tuğba Güler, Ocakoğlu, Gökhan, Korfalı, Ender, ABB-8161-2020, HPH-3049-2023, AAW-5254-2020, HLG-6346-2023, AAH-5180-2021, 25936798300, 56729201700, 15832295800, 7004641343 |
بيانات النشر: | Türk Nöroşirürji Derneği |
سنة النشر: | 2013 |
المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
مصطلحات موضوعية: | Neurosciences & neurology, Surgery, Aneursym, Postconditioning, Preconditioning, Temporary clipping, Giant intracranial aneurysms, Delayed neuronal death, Middle cerebral-artery, Ischemic tolerance, Vessel occlusion, Focal ischemia, Ischemia/reperfusion injury, Intraoperative-hypothermia, Intermittent reperfusion, Surgical-treatment, Brain, Brain ischemia, Humans, Intracranial aneurysm, Ischemic postconditioning, Ischemic preconditioning, Neurosurgical procedures, Reperfusion injury, Treatment outcome, Clinical neurology, Motor Evoked Potentials, Intraoperative Neurophysiological Monitoring, Adverse effects, Human |
الوصف: | Intracranial aneurysms and their treatment is one of the leading problems of neurosurgery that create high mortality and morbidity. The technique of safe clipping is as generally used depends on the temporary occlusion of the cerebral vasculature during surgery. However, there is no exact data about temporary clipping or timing of this procedure. Preconditioning by exposure to sublethal hypoxic stress, hours or days before severe hypoxia, decreases cell death, and this resistance of the brain to injury is known as ischemic tolerance. Brief alternating periods of reperfusion-reocclusion at the beginning of reperfusion is defined as postconditioning. Cerebral ischemic pre/postconditioning protects against stroke, but is clinically feasible only when the occurrence of stroke is predictable. Brief, repetitive occlusion and release of the main trunk of a vessel during early aneurysm surgery or before long-lasting temporary artery occlusion may protect the brain against later possible vasospasm/ischemia. |
نوع الوثيقة: | review |
وصف الملف: | application/pdf |
اللغة: | English |
تدمد: | 1019-5149 |
العلاقة: | Makale - Uluslararası Hakemli Dergi; Turkish Neurosurgery; Taşkapılıoğlu, M. Ö. vd. (2016). "Effect of pre/postconditioning at temporary clipping". Turkish Neurosurgery, 26(1), 1-7.; https://doi.org/10.5137/1019-5149.JTN.8263-13.1Test; http://www.turkishneurosurgery.org.tr/abstract.php?id=1631Test; http://hdl.handle.net/11452/33400Test; 000372668500001; 2-s2.0-84959558373; 26 |
DOI: | 10.5137/1019-5149.JTN.8263-13.1 |
الإتاحة: | https://doi.org/10.5137/1019-5149.JTN.8263-13.1Test http://hdl.handle.net/11452/33400Test http://www.turkishneurosurgery.org.tr/abstract.php?id=1631Test |
حقوق: | info:eu-repo/semantics/openAccess ; Atıf Gayri Ticari Türetilemez 4.0 Uluslararası ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
رقم الانضمام: | edsbas.A09A53E5 |
قاعدة البيانات: | BASE |
تدمد: | 10195149 |
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DOI: | 10.5137/1019-5149.JTN.8263-13.1 |