دورية أكاديمية

pmartR 2.0 : A Quality Control, Visualization, and Statistics Pipeline for Multiple Omics Datatypes

التفاصيل البيبلوغرافية
العنوان: pmartR 2.0 : A Quality Control, Visualization, and Statistics Pipeline for Multiple Omics Datatypes
المؤلفون: David J. Degnan (14351495), Kelly G. Stratton (4388506), Rachel Richardson (458168), Daniel Claborne (6269396), Evan A. Martin (10728369), Nathan A. Johnson (6910028), Damon Leach (14351498), Bobbie-Jo M. Webb-Robertson (46423), Lisa M. Bramer (1473334)
سنة النشر: 2023
مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Immunology, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, streamlined statistical purposes, present relevant examples, new feature benefits, made progress toward, labeled ), metabolomic, https :// github, transcriptomic data analyses, mass spectrometry data, lipidomic data sets, multiple omics datatypes, paired data, omics community, voom <, trelliscopejs <, trelliscopejs ), trellis displays, specific characteristics, r packages, quick creation, quality control, initial release, growing userbase
الوصف: The pmartR (https://github.com/pmartR/pmartRTest) package was designed for the quality control (QC) and analysis of mass spectrometry data, tailored to specific characteristics of proteomic (isobaric or labeled), metabolomic, and lipidomic data sets. Since its initial release, the tool has been expanded to address the needs of its growing userbase and now includes QC and statistics for nuclear magnetic resonance metabolomic data, and leverages the DESeq2 , edgeR , and limma-voom R packages for transcriptomic data analyses. These improvements have made progress toward a unified omics processing pipeline for ease of reporting and streamlined statistical purposes. The package’s statistics and visualization capabilities have also been expanded by adding support for paired data and by integrating pmartR with the trelliscopejs R package for the quick creation of trellis displays (https://github.com/hafen/trelliscopejsTest). Here, we present relevant examples of each of these enhancements to pmartR and highlight how each new feature benefits the omics community.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
العلاقة: https://figshare.com/articles/journal_contribution/_i_pmartR_2_0_i_A_Quality_Control_Visualization_and_Statistics_Pipeline_for_Multiple_Omics_Datatypes/21842030Test
DOI: 10.1021/acs.jproteome.2c00610.s002
الإتاحة: https://doi.org/10.1021/acs.jproteome.2c00610.s002Test
حقوق: CC BY-NC 4.0
رقم الانضمام: edsbas.9F849654
قاعدة البيانات: BASE