التفاصيل البيبلوغرافية
| العنوان: |
Risk factors for evaluating early mortality after microvascular reconstruction of head and neck cancers |
| المؤلفون: |
Nieminen, Teija, Tolvi, Morag, Lassus, Patrik, Wilkman, Tommy, Lehtonen, Lasse, Mäkitie, Antti |
| المساهمون: |
Anestesiologian yksikkö, HUS Perioperative, Intensive Care and Pain Medicine, Research Program in Systems Oncology, Korva-, nenä- ja kurkkutautien klinikka, HUS Head and Neck Center, HUS Musculoskeletal and Plastic Surgery, Clinicum, Faculty Common Matters (Faculty of Medicine), Oral and Maxillofacial Surgery, Plastiikkakirurgian yksikkö, HUSLAB, Department of Public Health, HUS Diagnostic Center, Helsinki University Hospital Area, Research Programs Unit |
| بيانات النشر: |
SAGE Publications Ltd STM |
| سنة النشر: |
2022 |
| المجموعة: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: |
Head and neck cancer, early mortality, head and neck surgery, microvascular free flap, postoperative complication, FREE TISSUE TRANSFER, POSTOPERATIVE COMPLICATIONS, ORAL-CAVITY, MAJOR HEAD, SURGERY, SURVIVAL, COMORBIDITY, MORBIDITY, 3122 Cancers, 3126 Surgery, anesthesiology, intensive care, radiology |
| الوصف: |
Background: Free tissue transfer reconstruction carries significant complication rates in surgical head and neck oncology. A registry-based approach offers a possibility to investigate the factors affecting increased morbidity and early mortality, that is, death within 6 months of treatment. Methods: A retrospective registry review was conducted on a series of 317 consecutive microvascular free tissue transfers in head and neck cancer patients performed during 2013-2017 at the Helsinki University Hospital (Helsinki, Finland). All surviving patients had a minimum follow-up of 2 years (range 24-84 months). Results: Overall, 36 (11.4%) early deaths occurred in this series. In multivariable logistic regression analysis, patients aged 75 years and older (p = 0.019), Adult Comorbidity Evaluation-27 (ACE-27) score of 3 (p = 0.048), tumor class T3 (p = 0.005), lymph node class N2 (p = 0.014), or thrombocyte count of 360 (x 10(9) L) or more (p = 0.001) were more likely to die within 6 months of surgery. Of these 36 patients, 27 (75%) had a complication warranting hospital care and most (n = 22, 61%) had several complications. Conclusions: Early postoperative mortality most frequently affects patients aged 75 years and above, with a high ACE-27 score, advanced tumor stage, or high thrombocyte count. Therefore, preoperative assessment and patient selection should have a crucial role in this patient population. ; Peer reviewed |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The work was supported by the Helsinki University Hospital Research Fund.; Nieminen , T , Tolvi , M , Lassus , P , Wilkman , T , Lehtonen , L & Mäkitie , A 2022 , ' Risk factors for evaluating early mortality after microvascular reconstruction of head and neck cancers ' , Scandinavian Journal of Surgery , vol. 111 , no. 4 , pp. 83-91 . https://doi.org/10.1177/14574969221117010Test; ORCID: /0000-0002-3443-3838/work/127503723; 0423f170-0ba1-4b38-bb78-3f8f0ef15237; http://hdl.handle.net/10138/350666Test; 000843878600001 |
| الإتاحة: |
http://hdl.handle.net/10138/350666Test |
| حقوق: |
cc_by ; openAccess ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.9F282E72 |
| قاعدة البيانات: |
BASE |
