التفاصيل البيبلوغرافية
| العنوان: |
Surgical Management of Chiari Malformation Type I Associated with Syringomyelia: Outcome of Surgeries Based on the New Classification and Study of Cerebrospinal Fluid Dynamics |
| المؤلفون: |
Misao Nishikawa, Toru Yamagata, Kentarou Naito, Noritsugu Kunihiro, Hiroaki Sakamoto, Mistuhiro Hara, Kenji Ohata, Takeo Goto |
| المصدر: |
Journal of Clinical Medicine; Volume 11; Issue 15; Pages: 4556 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Chiari malformation, syringomyelia, surgery, clinical outcome, cerebrospinal fluid, cerebrospinal fluid flow dynamics, posterior fossa decompression |
| الوصف: |
Introduction: The mainstay of treatment of syringomyelia associated with Chiari malformation type I (CM-I) is the management of CM-I to normalize the cerebrospinal fluid (CSF) flow at the foramen magnum. CM-I is classified into three independent types. Surgical treatment was selected based on the mechanism of hindbrain ptosis in each CM-I type. Materials and Methods: Foramen magnum decompression (FMD: 213 cases), expansive suboccipital cranioplasty (ESCP: 87 cases), and craniocervical fixation (CCF: 30 cases) were performed. CSF flow dynamics were assessed pre- and post-surgery using cine phase contrast magnetic resonance imaging. During surgery, CSF flow dynamics were examined using color Doppler ultrasonography (CDU). Results: ESCP and FMD demonstrated high rates of improvement in neurological symptoms and signs (82.7%), whereas CCF demonstrated a high rate of improvement in neurological symptoms (89%). The pre-operative maximum flow velocity (cm/s) was significantly lower in patients than in controls and increased post-operatively. During surgery, CDU indicated that the volume of the major cistern was 8 mL, and the maximum flow velocity was >3 mL/s. Conclusions: An appropriate surgical treatment should be selected for CM-I to correct hindbrain ptosis. In addition, it is necessary to confirm the normalization of CSF flow at the foramen of Magendie. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Clinical Neurology; https://dx.doi.org/10.3390/jcm11154556Test |
| DOI: |
10.3390/jcm11154556 |
| الإتاحة: |
https://doi.org/10.3390/jcm11154556Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.9EC63E9F |
| قاعدة البيانات: |
BASE |
