دورية أكاديمية

Farmers develop more aggressive histologic subtypes of basal cell carcinoma. Experience from a Tertiary Hospital in Northern Greece

التفاصيل البيبلوغرافية
العنوان: Farmers develop more aggressive histologic subtypes of basal cell carcinoma. Experience from a Tertiary Hospital in Northern Greece
المؤلفون: Apalla, Zoe, Lallas, Aimilios, Sotiriou, Eleni, Lazaridou, Elizabeth, Vakirlis, Efstratios, Trakatelli, Myrto Georgia, Kyrgidis, Athanassios, Ioannides, Demetrios
المصدر: JEADV. Journal of the European Academy of Dermatology and Venereology, 30
سنة النشر: 2016
المجموعة: DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB)
مصطلحات موضوعية: Dermatologie, Pathologie maladies infectieuses
الوصف: Background Ultraviolet radiation plays an important role in the pathogenesis of non-melanoma skin cancer. Outdoor workers, including farmers, experience higher exposure levels compared to the general population. Available literature data suggest that occupational ultraviolet exposure represents an independent risk factor for squamous cell carcinoma; whereas for basal cell carcinoma (BCC) this association still remains unclarified. Objectives To analyse the epidemiological, clinical and histological data of patients diagnosed with BCC, and correlate them with outdoor occupation in farmers. Methods Individuals with histologically diagnosed BCCs, between September 2013 and September 2015, were included in the study. Their medical data, including epidemiological, clinical and histological characteristics, were recorded and analysed in conjunction with the occupation. Farmers were identified based on their specific public health insurance. Results Three hundred and forty patients, with 542 BCCs were included in the study. One hundred and twenty (35.3%) were farmers. Mean age of farmers was lower than non-farmers (66.0 ± 9.1 years vs. 75 ± 6.6 years, Mann-Whitney U-test, P < 0.001). Farmers had a sixfold higher probability for exhibiting photodamaged skin (OR = 6.02, 95% CI: 3.66-9.90, P < 0.001). Farmer workers were more likely to exhibit infiltrative or morpheaform BCC, but less likely to develop superficial BCC. Conclusion Our results indicate a higher risk of earlier development of more aggressive histological subtypes of BCCs in farmers. Photodamage was also more common in this group. Primary and secondary prevention strategies focusing on outdoor workers, including farmers, are mandatory. ; SCOPUS: ar.j ; FLWIN ; info:eu-repo/semantics/published
نوع الوثيقة: article in journal/newspaper
وصف الملف: 1 full-text file(s): application/pdf
اللغة: English
العلاقة: uri/info:doi/10.1111/jdv.13605; uri/info:scp/84962521936; https://dipot.ulb.ac.be/dspace/bitstream/2013/231533/3/231533.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/231533Test
الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/231533Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/231533/3/231533.pdfTest
رقم الانضمام: edsbas.9D927616
قاعدة البيانات: BASE