دورية أكاديمية

A clinical case of early multifocal atherosclerosis complicated by acute coronary syndrome in a young man with ulcerative colitis ; Клинический случай раннего мультифокального атеросклероза, осложненного острым коронарным синдромом, у молодого мужчины с язвенным колитом

التفاصيل البيبلوغرافية
العنوان: A clinical case of early multifocal atherosclerosis complicated by acute coronary syndrome in a young man with ulcerative colitis ; Клинический случай раннего мультифокального атеросклероза, осложненного острым коронарным синдромом, у молодого мужчины с язвенным колитом
المؤلفون: L. V. Tarasova, N. Yu. Kucherova, Yu. V. Tsyganova, Л. В. Тарасова, Н. Ю. Кучерова, Ю. В. Цыганова
المصدر: Meditsinskiy sovet = Medical Council; № 18 (2023); 151-158 ; Медицинский Совет; № 18 (2023); 151-158 ; 2658-5790 ; 2079-701X
بيانات النشر: REMEDIUM GROUP Ltd.
سنة النشر: 2023
المجموعة: Medical Council (E-Journal) / Медицинский Совет
مصطلحات موضوعية: атерогенез, extraintestinal manifestations, cardiovascular complications, ischaemic heart disease, Crohn’s disease, еndothelium dysfunction, atherogenesis, внекишечные проявления, сердечно-сосудистые осложнения, ишемическая болезнь сердца, болезнь Крона, системное воспаление, эндотелиальная дисфункция
الوصف: Inflammatory bowel disease (IBD) is a chronic, relapsing, systemic and immune-mediated conditiondis that frequently involve extraintestinal manifestations. Latest studies showed increased risk of cardiovascular complications, which is the main cause of death in developed countries, in chronic inflammatory disorders, especially during IBD relapses. IBD patients are at increased risk of conditions such as early atherosclerosis, ischaemic heart disease, myocardial infarction, stroke, venous thrombosis, heart failure, аtrial fibrillation. Hypotheses for the mechanism underlying the association of IBD and atherosclerotic cardiovascular diseases include adverse effects of both the IBD itself (chronic inflammation, еndothelium dysfunction, dyslipidemia, thrombocytosis, gut microbiome dysfunction) and its treatment. The predominant role in atherogenesis is currently assigned to disruption of the endothelium. Endothelium plays an important role in physiologic regulation of vascular tone, cell adhesion, migration and resistance to thrombosis. Also, its dysfunction is associated with increased risk of atherosclerosis development. Early multifocal atherosclerosis is a serious complication of ulcerative colitis and can occur in young people without traditional cardiovascular risk factors. Untimely diagnosis, lack of pathogenetic treatment, correction of basic anti-inflammatory therapy and comprehensive consideration of a problem of high cardiovascular risk can lead to acute myocardial infarction and stroke and disability of a patient of working age. The authors present a case report of multifocal atherosclerosis complicated by acute coronary syndrome in a young man with ulcerative colitis, who required a radical revision of the therapy. ; Воспалительные заболевания кишечника (ВЗК), к которым относится язвенный колит и болезнь Крона, – это хронические рецидивирующие системные и иммуноопосредованные состояния, часто сопровождающиеся внекишечными проявлениями. Последние исследования показали повышенный риск сердечно-сосудистых ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: Russian
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DOI: 10.21518/ms2023-306
الإتاحة: https://doi.org/10.21518/ms2023-306Test
https://doi.org/10.1093/ibd/izx089Test
https://doi.org/10.1111/bph.14975Test
https://doi.org/10.1016/j.tcm.2015.04.001Test
https://doi.org/10.3390/nu12051434Test
https://doi.org/10.26442/00403660.2022.02.201367Test
https://doi.org/10.3390/diseases10040073Test
https://doi.org/10.1111/apt.17162Test
https://doi.org/10.1016/j.avsg.2018.12.079Test
https://doi.org/10.1371/journal.pone.0056944Test
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رقم الانضمام: edsbas.9D4FDF1D
قاعدة البيانات: BASE