دورية أكاديمية

Dietary carbohydrate intake, plasma adipokine concentration and risk of breast cancer

التفاصيل البيبلوغرافية
العنوان: Dietary carbohydrate intake, plasma adipokine concentration and risk of breast cancer
المؤلفون: Shin, Hye Lim, Kim, Jeongseon, Sung, Mi‐Kyung
المصدر: The FASEB Journal ; volume 25, issue S1 ; ISSN 0892-6638 1530-6860
بيانات النشر: Wiley
سنة النشر: 2011
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: Dietary carbohydrate intake and obesity are suggested as risk factors for postmenopausal breast cancer. The study was conducted to determine whether carbohydrate quality measured by glycemic index(GI) and glycemic load(GL), and plasma adipokine concentration account for breast cancer risk. Breast cancer patients (n=263) and hospital‐based control subjects (n=263) were recruited from National Cancer Center, Korea. GI and GL were calculated based on food frequency questionnaires, and plasma concentrations of adiponectin and leptin were determined. Study results indicated that the GI(p=0.037) and GL(p=0.045) values were negatively associated with plasma adiponectin concentration while GL (p=0.028) was positively associated with plasma leptin concentration. There was a significant association between GI (OR = 6.06, 95% CI=2.24–16.37, p=0.0029), and GL (OR=4.42, 95% CI=1.59–12.28, p=0.0191) with breast cancer risk in postmenopausal women. The associations between GI, GL and breast cancer were more evident in subjects with lower plasma adiponection. This study was funded by Korean Science and Engineering Foundation (R01‐2007‐000‐11293‐0).
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1096/fasebj.25.1_supplement.978.4
الإتاحة: https://doi.org/10.1096/fasebj.25.1_supplement.978.4Test
حقوق: http://onlinelibrary.wiley.com/termsAndConditions#vorTest
رقم الانضمام: edsbas.9C37A309
قاعدة البيانات: BASE
الوصف
DOI:10.1096/fasebj.25.1_supplement.978.4