دورية أكاديمية
No impact of tDCS on stress-induced state rumination and no influence of executive control and trait rumination: A double-blind sham-controlled within-subjects study
| العنوان: | No impact of tDCS on stress-induced state rumination and no influence of executive control and trait rumination: A double-blind sham-controlled within-subjects study |
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| المؤلفون: | Hoebeke, Yorgo, Vanderhasselt, Marie-Anne, Carême, Marion, Maurage, Pierre, Heeren, Alexandre |
| المساهمون: | UCL - SSH/IPSY - Psychological Sciences Research Institute |
| المصدر: | Clinical Neuropsychiatry : journal of treatments evaluation, Vol. 21, no.1, p. 99-109 (2024) |
| بيانات النشر: | GiovanniFioriti Editore |
| سنة النشر: | 2024 |
| المجموعة: | DIAL@USL-B (Université Saint-Louis, Bruxelles) |
| مصطلحات موضوعية: | tDCS, brain stimulation, neuromodulation, rumination, depression, stress, clinical psychology |
| الوصف: | Objective: Rumination is conceptualized as a critical transdiagnostic vulnerability and maintenance factor for affective dysregulation and related emotional disorders. Recent research has pointed to transcranial direct current stimulation (tDCS) as a novel therapeutic tool for alleviating rumination, especially stress-induced rumination. However, the mechanisms of action underlying this effect remain unclear, particularly regarding the potential moderating role of executive control and trait-like rumination. Therefore, in this study, we investigated the impact of anodal tDCS on stress-induced rumination and the potential moderating influence of executive control and trait-like rumination on this effect. Method: Forty participants from the general community (i.e., unselected sample) took part in a double-blind within-subjects design study wherein we compared anodal stimulation over the left dorsolateral prefrontal cortex(dlPFC) with a sham-stimulation procedure. Participants completed an N-back task, reflecting executive control, during tDCS stimulation, followed by a stress-induction protocol wherein we assessed stress- induced state rumination. Results: We found no significant effect of tDCS on stress-induced state rumination and no modulation by executive control or trait rumination. Post-hoc Bayesian analyses corroborated these results and even supported the hypothesis that anodal tDCS does not impact stress-induced rumination. Conclusions: From a clinical perspective, our results are at odds with the current outlook that tDCS is a viable tool for reducing rumination, particularly stress-induced rumination. However, we firmly believe that the results of null-finding studies, such as those from this study, are particularly valuable for future iterations and meta-research on tDCS as a potential tool for targeting transdiagnostic processes, such as rumination. We also addressed methodological limitations and directions for future research in this area. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1724-4935 |
| العلاقة: | boreal:285773; http://hdl.handle.net/2078.1/285773Test; urn:ISSN:1724-4935; urn:EISSN:1724-4935 |
| DOI: | 10.36131/cnfioritieditore20240107 |
| الإتاحة: | https://doi.org/10.36131/cnfioritieditore20240107Test http://hdl.handle.net/2078.1/285773Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.9B950015 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17244935 |
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| DOI: | 10.36131/cnfioritieditore20240107 |