دورية أكاديمية
Stand‐alone model for delivery of oral HIV pre‐exposure prophylaxis in Kenya: a single‐arm, prospective pilot evaluation
| العنوان: | Stand‐alone model for delivery of oral HIV pre‐exposure prophylaxis in Kenya: a single‐arm, prospective pilot evaluation |
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| المؤلفون: | Katrina F. Ortblad, Peter Mogere, Victor Omollo, Alexandra P. Kuo, Magdaline Asewe, Stephen Gakuo, Stephanie Roche, Mary Mugambi, Melissa Latigo Mugambi, Andy Stergachis, Josephine Odoyo, Elizabeth A. Bukusi, Kenneth Ngure, Jared M. Baeten |
| المصدر: | Journal of the International AIDS Society, Vol 26, Iss 6, Pp n/a-n/a (2023) |
| بيانات النشر: | Wiley |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | differentiated service delivery (DSD), HIV prevention, Kenya, pre‐exposure prophylaxis (PrEP), private pharmacies, retention, Immunologic diseases. Allergy, RC581-607 |
| الوصف: | Introduction The delivery of daily, oral HIV pre‐exposure prophylaxis (PrEP) at private pharmacies may overcome barriers to PrEP delivery at public healthcare facilities, including HIV‐associated stigma, long wait times and overcrowding. Methods At five private, community‐based pharmacies in Kenya, a care pathway for PrEP delivery (ClinicalTrials.gov: NCT04558554) was piloted—the first of its kind in Africa. Pharmacy providers screened clients interested in PrEP for HIV risk, then used a prescribing checklist to identify clients without medical conditions that might contraindicate PrEP safety, counsel them on PrEP use and safety, conduct provider‐assisted HIV self‐testing and dispense PrEP. For complex clinical cases, a remote clinician was available for consultation. Clients who did not meet the checklist criteria were referred to public facilities for free services delivered by clinicians. Pharmacy providers dispensed a 1‐month PrEP supply at initiation and a 3‐month supply thereafter at a client fee of 300 KES (∼$3 USD) per visit. Results From November 2020 to October 2021, pharmacy providers screened 575 clients, identified 476 who met the prescribing checklist criteria and initiated 287 (60%) on PrEP. Among pharmacy PrEP clients, the median age was 26 years (IQR 22–33) and 57% (163/287) were male. The prevalence of behaviours associated with HIV risk among clients was high; 84% (240/287) reported sexual partners with unknown HIV status and 53% (151/287) reported multiple sexual partners (past 6 months). PrEP continuation among clients was 53% (153/287) at 1 month, 36% (103/287) at 4 months and 21% (51/242) at 7 months. During the pilot observation period, 21% (61/287) of clients stopped and restarted PrEP and overall pill coverage was 40% (IQR 10%–70%). Nearly, all pharmacy PrEP clients (≥96%) agreed or strongly agreed with statements regarding the acceptability and appropriateness of pharmacy‐delivered PrEP services. Conclusions Findings from this pilot suggest that populations at HIV risk ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1758-2652 |
| العلاقة: | https://doi.org/10.1002/jia2.26131Test; https://doaj.org/toc/1758-2652Test; https://doaj.org/article/ebac6c9157994871bd9d19bc993b0b3dTest |
| DOI: | 10.1002/jia2.26131 |
| الإتاحة: | https://doi.org/10.1002/jia2.26131Test https://doaj.org/article/ebac6c9157994871bd9d19bc993b0b3dTest |
| رقم الانضمام: | edsbas.99B95203 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17582652 |
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| DOI: | 10.1002/jia2.26131 |