دورية أكاديمية
Acute-on-chronic liver failure in patients with alcohol-related liver disease
| العنوان: | Acute-on-chronic liver failure in patients with alcohol-related liver disease |
|---|---|
| المؤلفون: | Gustot, T, Kamath, P, Jalan, R |
| المصدر: | Journal of Hepatology , 70 (2) pp. 319-327. (2019) |
| سنة النشر: | 2019 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Cirrhosis, Organ failure, Inflammation, Alcoholic hepatitis, Infection, Liver transplantation |
| الوصف: | The spectrum of alcohol-related liver diseases (ALD) includes steatosis, steatohepatitis, progressive liver fibrosis, and cirrhosis. Acute-on-chronic liver failure (ACLF) is a recently defined entity that occurs in patients with chronic liver diseases and is characterised by acute decompensation, organ failures and a high risk of short-term mortality. Active alcohol consumption, alcoholic hepatitis and bacterial infections are the most frequent events precipitating the development of ACLF in the context of ALD (ALD-ACLF). The specific management of this entity remains unknown and the place of salvage liver transplantation controversial. This overview details the current knowledge on specific aspects of epidemiology, pathophysiology, prognosis and management of ALD-ACLF. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://discovery.ucl.ac.uk/id/eprint/10064967/1/Acute-on-Chronic%20Liver%20Failure%20in%20Patients%20with%20Alcoholic%20Liver%20Diseases.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10064967Test/ |
| الإتاحة: | https://discovery.ucl.ac.uk/id/eprint/10064967/1/Acute-on-Chronic%20Liver%20Failure%20in%20Patients%20with%20Alcoholic%20Liver%20Diseases.pdfTest https://discovery.ucl.ac.uk/id/eprint/10064967Test/ |
| حقوق: | open |
| رقم الانضمام: | edsbas.9910DCF6 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |