Fluorescent and water dispersible single‐chain nanoparticles : core‐shell structured compartmentation

التفاصيل البيبلوغرافية
العنوان:	Fluorescent and water dispersible single‐chain nanoparticles : core‐shell structured compartmentation
المؤلفون:	Hoffmann, Justus F., Roos, Andreas H., Schmitt, Franz-Josef, Hinderberger, Dariush, Binder, Wolfgang H.
سنة النشر:	2021
المجموعة:	Share it - Open Access und Forschungsdaten-Repositorium der Hochschulbibliotheken in Sachsen-Anhalt
مصطلحات موضوعية:	ddc:540
الوصف:	Single-chain nanoparticles (SCNPs) are highly versatile structures resembling proteins, able to function as catalysts or biomedical delivery systems. Based on their synthesis by single-chain collapse into nanoparticular systems, their internal structure is complex, resulting in nanosized domains preformed during the crosslinking process. In this study we present proof of such nanocompartments within SCNPs via a combination of electron paramagnetic resonance (EPR) and fluorescence spectroscopy. A novel strategy to encapsulate labels within these water dispersible SCNPs with hydrodynamic radii of ≈5 nm is presented, based on amphiphilic polymers with additional covalently bound labels, attached via the copper catalyzed azide/alkyne “click” reaction (CuAAC). A detailed profile of the interior of the SCNPs and the labels’ microenvironment was obtained via electron paramagnetic resonance (EPR) experiments, followed by an assessment of their photophysical properties. ; Publikationsfond MLU
نوع الوثيقة:	article in journal/newspaper
وصف الملف:	application/pdf
اللغة:	English
ردمك:	978-1-74939-672-2 1-74939-672-6
العلاقة:	http://dx.doi.org/10.25673/38490Test; https://opendata.uni-halle.de//handle/1981185920/38736Test
DOI:	10.25673/38490
الإتاحة:	https://doi.org/10.25673/38490Test https://opendata.uni-halle.de//handle/1981185920/38736Test
حقوق:	https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام:	edsbas.98FD1174
قاعدة البيانات:	BASE

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الوصف
ردمك:	9781749396722 1749396726
DOI:	10.25673/38490