دورية أكاديمية

Prevalence and molecular characterization of canine parvovirus-2 in dogs in Giza Governorate, Egypt

التفاصيل البيبلوغرافية
العنوان: Prevalence and molecular characterization of canine parvovirus-2 in dogs in Giza Governorate, Egypt
المؤلفون: Mekky, Reham H., Shoulah, Salma, Moustafa, Abdelmoneim, Selim, Abdelfattah, Marawan, Marawan A.
المصدر: Journal of Advanced Veterinary Research; Vol. 14 No. 2 (2024): Special Issue (Veterinary Medicine and Food Safety Challenges); 253-256 ; 2090-6277 ; 2090-6269
بيانات النشر: Journal of Advanced Veterinary Research
سنة النشر: 2024
المجموعة: Journal of Advanced Veterinary Research (University Assiut, Egypt)
مصطلحات موضوعية: CPV-2, SNAP test, Sequencing, VP2 gene, Phylogenetic analysis
الوصف: Canine parvovirus type-2 (CPV-2) is one of the most common diseases affecting dogs. The disease has been reported worldwide including Egypt causing both acute hemorrhagic enteritis and myocarditis in the infected dogs. Two distinct parvoviruses are incriminated in the disease occurrence CPV-1 and CPV-2. However, the CPV-2 is the most pathogenic and includes three antigenic variants namely, CPV2a, CPV2b and CPV2c. Since the molecular characterization of CPV is critical for future disease prevention and control, the current study aimed to determine the prevalence of CPV-2 in dogs in Giza governorate, Egypt, and molecular characterization of circulating CPV-2. A total of 300 stool samples were collected from dogs with clinical signs suggestive of canine parvovirus from different veterinary hospitals and clinics in Giza governorate, during the period from January 2022 to December 2022. The overall prevalence of CPV-2 in dogs was 72.67% and it was significantly associated with breed, sex and age of examine dogs. In addition, the sequencing and phylogenetic analysis of circulating CPV-2 based on VP2 gene revealed that the circulating strain is CPV-2c. The present findings suggest that the failure of vaccination may be attributed to the use of CPV-2b commercial vaccines in areas where CPV-2c is prevalent.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://www.advetresearch.com/index.php/AVR/article/view/1519/1117Test; https://www.advetresearch.com/index.php/AVR/article/view/1519Test
الإتاحة: https://www.advetresearch.com/index.php/AVR/article/view/1519Test
حقوق: Copyright (c) 2024 Journal of Advanced Veterinary Research ; https://creativecommons.org/licenses/by-nc-nd/4.0Test
رقم الانضمام: edsbas.989CDF3C
قاعدة البيانات: BASE