دورية أكاديمية

Acute Kidney Injury after Heart Valve Surgery in Elderly Patients: any Risk Factors to Modify?

التفاصيل البيبلوغرافية
العنوان: Acute Kidney Injury after Heart Valve Surgery in Elderly Patients: any Risk Factors to Modify?
المؤلفون: Carrascal,Yolanda, Laguna,Gregorio, Blanco,Miriam, Pañeda,Lucia, Segura,Bárbara
المصدر: Brazilian Journal of Cardiovascular Surgery n.ahead 2020
بيانات النشر: Sociedade Brasileira de Cirurgia Cardiovascular
سنة النشر: 2020
المجموعة: SciELO Brazil (Scientific Electronic Library Online)
مصطلحات موضوعية: Cardiac Surgical Procedures - adverse effects, Cardiopulmonary Bypass, Risk Factors, Anemia, Acute Kidney Injury, Aged
الوصف: Introduction: Postoperative acute kidney injury contributes to longer hospital stays and increased costs related to cardiac surgery in the elderly. We analyse the influence of the patient’s age on risk factors for acute kidney injury after cardiac valve surgery. Methods: We evaluated the prevalence and risk factors for acute kidney injury in 939 consecutive patients undergoing valve surgery, between 2013 and 2018. Results: The prevalence of acute kidney injury was 19.5%. Hypertension (P=0.017); RR (95% CI): 1.74 (1.10-3.48), age ≥70 years (P=0.006); RR (95% CI): 1.79 (1.17-2.72), preoperative haematocrit <33% (P=0.009); RR (95% CI): 2.04 (1.19-3.48), glomerular filtration rate <60 ml/min/1.73 m2 (P<0.0001); RR (95%) CI: 2.36 (1.54-3.62) and cardiac catheterization <8 days before surgery (P=0.021); RR (95% CI): 2.15 (1.12-4.11) were identified as independent risk factors. In patients older than 70 years, with no kidney disease diagnosed preoperatively, glomerular filtration rate <70 ml/min/1.73 m2, male gender, cardiopulmonary bypass time, preoperative haematocrit <36% and preoperative therapy with angiotensin-converting enzyme inhibitors were risk factors for acute kidney injury after valve surgery. Conclusions: In elderly patients, postoperative acute kidney injury develops with higher values of preoperative glomerular filtration rate than those observed in a younger population. Preoperative correction of anaemia, discontinuation of angiotensin-converting enzyme inhibitors and surgical techniques reducing cardiopulmonary bypass time would be considered to reduce the prevalence of renal failure.
نوع الوثيقة: article in journal/newspaper
وصف الملف: text/html
اللغة: English
الإتاحة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382020005009204Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.97DE88B0
قاعدة البيانات: BASE