دورية أكاديمية
Antioxidants in Pregnancy:Do We Really Need More Trials?
| العنوان: | Antioxidants in Pregnancy:Do We Really Need More Trials? |
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| المؤلفون: | Di Fabrizio, Carolina, Giorgione, Veronica, Khalil, Asma, Murdoch, Colin E. |
| المصدر: | Di Fabrizio , C , Giorgione , V , Khalil , A & Murdoch , C E 2022 , ' Antioxidants in Pregnancy : Do We Really Need More Trials? ' , Antioxidants , vol. 11 , no. 5 , 812 . https://doi.org/10.3390/antiox11050812Test |
| سنة النشر: | 2022 |
| المجموعة: | Discovery - University of Dundee Online Publications |
| مصطلحات موضوعية: | antioxidants, oxidative stress, preeclampsia, pregnancy, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1314, name=Physiology, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology |
| الوصف: | Human pregnancy can be affected by numerous pathologies, from those which are mild and reversible to others which are life-threatening. Among these, gestational diabetes mellitus and hypertensive disorders of pregnancy with subsequent consequences stand out. Health problems experienced by women during pregnancy and postpartum are associated with significant costs to health systems worldwide and contribute largely to maternal mortality and morbidity. Major risk factors for mothers include obesity, advanced maternal age, cardiovascular dysfunction, and endothelial damage; in these scenarios, oxidative stress plays a major role. Markers of oxidative stress can be measured in patients with preeclampsia, foetal growth restriction, and gestational diabetes mellitus, even before their clinical onset. In consequence, antioxidant supplements have been proposed as a possible therapy; however, results derived from large scale randomised clinical trials have been disappointing as no positive effects were demonstrated. This review focuses on the latest evidence on oxidative stress in pregnancy complications, their early diagnosis, and possible therapies to prevent or treat these pathologies. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://discovery.dundee.ac.uk/en/publications/33deba1c-8e32-494e-945b-5eab2c3a32c3Test |
| DOI: | 10.3390/antiox11050812 |
| الإتاحة: | https://doi.org/10.3390/antiox11050812Test https://discovery.dundee.ac.uk/en/publications/33deba1c-8e32-494e-945b-5eab2c3a32c3Test https://discovery.dundee.ac.uk/ws/files/74498585/antioxidants_11_00812.pdfTest http://www.scopus.com/inward/record.url?scp=85128730615&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.95D9E771 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/antiox11050812 |
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