التفاصيل البيبلوغرافية
العنوان: |
The Need for Additional Surgery after Passive versus Active Approaches to Syndromic Craniosynostosis: A Meta-analysis |
المؤلفون: |
Grosser, Joshua A., Kogan, Samuel, Layton, Ryan G., Pontier, Joshua F., Bins, Griffin P., Runyan, Christopher M. |
المصدر: |
Plastic and Reconstructive Surgery - Global Open ; volume 11, issue 3, page e4891 ; ISSN 2169-7574 |
بيانات النشر: |
Ovid Technologies (Wolters Kluwer Health) |
سنة النشر: |
2023 |
الوصف: |
Background: Endoscopically assisted craniofacial surgery (EACS) has numerous advantages over traditional, open approaches, such as fronto-orbital advancement in treating nonsyndromic craniosynostosis. However, several articles report high reoperation rates in syndromic patients treated with EACS. This meta-analysis and review examines undesirable outcome rates (UORs), defined as reoperation or Whitaker category III/IV, in syndromic patients undergoing primary EACS compared with procedures that actively expand the cranial vault. Methods: PubMed and Embase were searched in June 2022 to identify all articles reporting primary reoperation or Whitaker outcomes for syndromic patients undergoing cranial vault expanding surgery or suturectomy. A meta-analysis of proportions was performed comparing UORs, and a trim-and-fill adjustment method was used to validate sensitivity and assess publication bias. Results: A total of 721 articles were screened. Five EACS articles (83 patients) and 22 active approach articles (478 patients) met inclusion criteria. Average UORs for EACS and active approaches were 26% (14%–38%) and 20% (13%–28%), respectively ( P = 0.18). Reoperation occurred earlier in EACS patients (13.7 months postprimary surgery versus 37.1 months for active approaches, P = 0.003). Relapse presentations and reason for reoperation were also reviewed. Subjectively, EACS UORs were higher in all syndromes except Apert, and Saethre-Chotzen patients had the highest UOR for both approaches. Conclusions: There was no statistically significant increase in UORs among syndromic patients treated with EACS compared with traditional approaches, although EACS patients required revision significantly sooner. Uncertainties regarding the long-term efficacy of EACS in children with syndromic craniosynostosis should be revisited as more data become available. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1097/gox.0000000000004891 |
DOI: |
10.1097/GOX.0000000000004891 |
الإتاحة: |
https://doi.org/10.1097/gox.0000000000004891Test |
حقوق: |
http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
رقم الانضمام: |
edsbas.93C4FDCF |
قاعدة البيانات: |
BASE |