دورية أكاديمية
Prone Position in COVID-19 and -COVID-19 Acute Respiratory Distress Syndrome: An International Multicenter Observational Comparative Study
| العنوان: | Prone Position in COVID-19 and -COVID-19 Acute Respiratory Distress Syndrome: An International Multicenter Observational Comparative Study |
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| المؤلفون: | Camporota, L., Sanderson, B., Chiumello, D., Terzi, N., Argaud, L., Rimmelé, T., Metuor, R., Verstraete, A., Cour, M., Bohé, J., Piriou, V., Beuret, P., Guérin, C. |
| المساهمون: | Guy's and St Thomas' Hospital London, King‘s College London, Università degli Studi di Milano = University of Milan (UNIMI), Université Grenoble Alpes (UGA), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Edouard Herriot CHU - HCL, Hospices Civils de Lyon (HCL), Service de Médecine Intensive et Réanimation Lyon (MIR), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Centre Hospitalier de Roanne |
| المصدر: | ISSN: 0090-3493. |
| بيانات النشر: | HAL CCSD Lippincott, Williams & Wilkins |
| سنة النشر: | 2022 |
| المجموعة: | Université de Lyon: HAL |
| مصطلحات موضوعية: | Humans, Aged, Male, Female, Middle Aged, Retrospective Studies, Intensive Care Units, Europe, Patient Positioning, Odds Ratio, Prone Position, COVID-19/complications/physiopathology/*therapy, Lung/physiopathology, Respiration, Artificial/*methods, Respiratory Distress Syndrome/etiology/physiopathology/*therapy, Respiratory Function Tests, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Objectives: Prone position is used in acute respiratory distress syndrome and in coronavirus disease 2019 acute respiratory distress syndrome. However, it is unclear how responders may be identified and whether an oxygenation response improves outcome. The objective of this study was to quantify the response to prone position, describe the differences between coronavirus disease 2019 acute respiratory distress syndrome and acute respiratory distress syndrome, and explore variables associated with survival.Design: Retrospective, observational, multicenter, international cohort study.Setting: Seven ICUs in Italy, United Kingdom, and France.Patients: Three hundred seventy-six adults (220 coronavirus disease 2019 acute respiratory distress syndrome and 156 acute respiratory distress syndrome).Intervention: None.Measurements and main results: Preproning, a greater proportion of coronavirus disease 2019 acute respiratory distress syndrome patients had severe disease (53% vs 40%), worse Pao2/Fio2 (13.0 kPa [interquartile range, 10.5-15.5 kPa] vs 14.1 kPa [interquartile range, 10.5-18.6 kPa]; p = 0.017) but greater compliance (38 mL/cm H2O [interquartile range, 27-53 mL/cm H2O] vs 31 mL/cm H2O [interquartile range, 21-37 mL/cm H2O]; p < 0.001). Patients with coronavirus disease 2019 acute respiratory distress syndrome had a longer median time from intubation to prone position (2.0 d [interquartile range, 0.7-5.0 d] vs 1.0 d [interquartile range, 0.5-2.9 d]; p = 0.03). The proportion of responders, defined by an increase in Pao2/Fio2 greater than or equal to 2.67 kPa (20 mm Hg), upon proning, was similar between acute respiratory distress syndrome and coronavirus disease 2019 acute respiratory distress syndrome (79% vs 76%; p = 0.5). Responders had earlier prone position (1.4 d [interquartile range, 0.7-4.2 d] vs 2.5 d [interquartile range, 0.8-6.2 d]; p = 0.06)]. Prone position less than 24 hours from intubation achieved greater improvement in oxygenation (11 kPa [interquartile range, 4-21 ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34582426; inserm-03755200; https://inserm.hal.science/inserm-03755200Test; https://inserm.hal.science/inserm-03755200/documentTest; https://inserm.hal.science/inserm-03755200/file/Prone_Position_in_COVID_19_and__COVID_19_Acute.11.pdfTest; PUBMED: 34582426; PUBMEDCENTRAL: PMC8923275 |
| DOI: | 10.1097/ccm.0000000000005354 |
| الإتاحة: | https://doi.org/10.1097/ccm.0000000000005354Test https://inserm.hal.science/inserm-03755200Test https://inserm.hal.science/inserm-03755200/documentTest https://inserm.hal.science/inserm-03755200/file/Prone_Position_in_COVID_19_and__COVID_19_Acute.11.pdfTest |
| رقم الانضمام: | edsbas.92FDC929 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/ccm.0000000000005354 |
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