دورية أكاديمية

Misconceptions and beliefs around hormone replacement therapy after childhood hematopoietic stem cell transplantation: A qualitative study among women leukemia survivors

التفاصيل البيبلوغرافية
العنوان: Misconceptions and beliefs around hormone replacement therapy after childhood hematopoietic stem cell transplantation: A qualitative study among women leukemia survivors
المؤلفون: Vergier, Julia, Reynaud, Rachel, Michel, Gerard, Auquier, Pascal, Courbiere, Blandine
المساهمون: Hôpital de la Timone CHU - APHM (TIMONE), Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Marseille Maladies Rares (MarMaRa), Aix Marseille Université (AMU), Assistance Publique - Hôpitaux de Marseille (APHM), Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement IRD : UMR237-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 1932-6203.
بيانات النشر: HAL CCSD
Public Library of Science
سنة النشر: 2023
المجموعة: Université d'Avignon et des Pays de Vaucluse: HAL
مصطلحات موضوعية: Cancer treatment, Hematopoietic stem cell transplantation, Leukemia, Cancer chemotherapy, Hormone replacement therapy, Puberty, Acute lymphoblastic leukemia, Pediatric oncology, [SDV.GEN]Life Sciences [q-bio]/Genetics
الوصف: International audience ; PurposeAfter childhood leukemia and hematopoietic stem cell transplantation, hormone replacement therapy is often required to induce puberty because of premature ovarian insufficiency. Observance of this kind of treatment in adolescents and young women seems quite poor, and literature about its acceptance remains scarce; in order to learn about their experience and to better understand their attitude towards hormone replacement therapy, we used qualitative methods.Design and patients13 young women childhood cancer survivors completed an individual interview.ResultsWe report that the negative experience of leukemia may cause rejection of the treatment, closely related to infertility unacceptance. Misconceptions and lack of adequate information of hormonal treatment effects are also major barriers to a good compliance.Conclusions and implications for cancer survivorsObservance of hormone replacement therapy for young women childhood cancer survivors can be improved with a confidential patient-physician relationship, patient education, choice of galenic formulation according to personal preference, and psychological support during the long-time follow up.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: hal-04254103; https://amu.hal.science/hal-04254103Test; https://amu.hal.science/hal-04254103/documentTest; https://amu.hal.science/hal-04254103/file/327161ea4e68850ea1a4f6a2650d4080.pdfTest
DOI: 10.1371/journal.pone.0283940
الإتاحة: https://doi.org/10.1371/journal.pone.0283940Test
https://amu.hal.science/hal-04254103Test
https://amu.hal.science/hal-04254103/documentTest
https://amu.hal.science/hal-04254103/file/327161ea4e68850ea1a4f6a2650d4080.pdfTest
حقوق: http://creativecommons.org/licenses/byTest/ ; info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.8F619F7F
قاعدة البيانات: BASE