التفاصيل البيبلوغرافية
| العنوان: |
Metabolism of metronidazole in humans. |
| المؤلفون: |
Nina Zemanová (11668742), Kateřina Lněničková (11668745), Markéta Vavrečková (11668748), Eva Anzenbacherová (11668751), Pavel Anzenbacher (520123), Iveta Zapletalová (11668754), Petra Hermanová (11668757), Tomáš Hudcovic (3151017), Hana Kozáková (4858504), Lenka Jourová (11668760) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Microbiology, Genetics, Physiology, Pharmacology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, selected cytochromes p450, remain mostly elusive, recent studies indicate, gut microbiota may, altered gut microbiota, +microbiome%22">xlink "> microbiome, gut microbiome modulates, gut microbiome affects, significant metabolic organ, shown lower level, drug metabolizing enzymes, gut microbiome, significant interaction, parent drug, biotransformation enzymes, vice versa, results hence, reported earlier, pharmacotherapy interventions, mutual relationship, murine plasma, molecular mechanisms |
| الوصف: |
In the human liver, metronidazole is metabolized by side-chain hydroxylation, oxidation or glucuronidation to form more polar metabolites. Metronidazole can also undergo modification by gut microbiota producing reduced metabolites such as N-(2-hydroxyethyl)-oxamic acid and acetamide. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/figure/Metabolism_of_metronidazole_in_humans_/16965977Test |
| DOI: |
10.1371/journal.pone.0259643.g001 |
| الإتاحة: |
https://doi.org/10.1371/journal.pone.0259643.g001Test |
| حقوق: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.8EA5DBCD |
| قاعدة البيانات: |
BASE |
