التفاصيل البيبلوغرافية
| العنوان: |
Subcutaneous interferon beta-1a administration by electronic auto-injector is associated with high adherence in patients with relapsing remitting multiple sclerosis in a real-life study |
| المؤلفون: |
Jarvinen, Elina, Multanen, Juha, Atula, Sari |
| المساهمون: |
Neurologian yksikkö, Clinicum, HUS Neurocenter |
| بيانات النشر: |
MDPI |
| سنة النشر: |
2019 |
| المجموعة: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: |
Relapsing remitting multiple sclerosis, Adherence, Auto-injector, Interferon beta-1a, LONG-TERM ADHERENCE, SELF-INJECTION, SINGLE-ARM, OPEN-LABEL, PHASE-IV, MULTICENTER, DEVICE, TOLERABILITY, AUTOINJECTION, REBISMART(R), 3112 Neurosciences, 3124 Neurology and psychiatry |
| الوصف: |
The objective was to investigate adherence measured by an electronic auto-injector device, and self-reported adherence and treatment convenience in subjects with relapsing remitting multiple sclerosis (RRMS), using an electronic auto-injector Rebismart (R) to self-inject interferon beta-1a. Thirty one patients with RRMS using the electronic auto-injector Rebismart (R) for selfinjecting interferon beta-1a subcutaneously three times weekly were included in a reallife clinical multicenter study for 24 weeks in Finland. Mean adherence reported by the device and mean self-assessment of adherence were studied. Reasons for missing injections and treatment convenience were assessed. Association between adherence and gender and age were studied. The mean adherence calculated from the device data was 93.5%. The mean self-assessment of adherence was 96.6%. The most common reason for missing an injection was forgetfulness. Adherence (measured by the device) was not changed over time. In the high adherence group there were more females and young patients (<30 years of age). The auto-injector was found to substantially ease the treatment by 90% of the patients. The electronic auto-injector was associated with high adherence to treatment. The device was found to ease the patient's treatment and it was perceived as easy to use. It is a convenient tool to assess patient's adherence to treatment. ; Peer reviewed |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
funding for this work was provided by Merck Finland, a business of Merck KGaA, Darmstadt, Germany.; Jarvinen , E , Multanen , J & Atula , S 2017 , ' Subcutaneous interferon beta-1a administration by electronic auto-injector is associated with high adherence in patients with relapsing remitting multiple sclerosis in a real-life study ' , Neurology international , vol. 9 , no. 1 , 6957 . https://doi.org/10.4081/ni.2017.6957Test; http://hdl.handle.net/10138/299326Test; 4296721a-c2af-496e-901f-962c8afe4284; 85015440526; 000396573700002 |
| الإتاحة: |
http://hdl.handle.net/10138/299326Test |
| حقوق: |
cc_by_nc ; info:eu-repo/semantics/openAccess ; openAccess |
| رقم الانضمام: |
edsbas.8E2B58B3 |
| قاعدة البيانات: |
BASE |
