التفاصيل البيبلوغرافية
العنوان: |
An Experimental Adult Zebrafish Model for Shigella Pathogenesis, Transmission, and Vaccine Efficacy Studies |
المؤلفون: |
Howlader, Debaki R., Bhaumik, Ushasi, Halder, Prolay, Satpathy, Aishwarya, Sarkar, Sounak, Ghoshal, Mrinalini, Maiti, Suhrid, Withey, Jeffrey H., Mitobe, Jiro, Dutta, Shanta, Koley, Hemanta |
المساهمون: |
Brissette, Catherine Ayn, Indian Council of Medical Research, CSIR | CSIR |
المصدر: |
Microbiology Spectrum ; volume 10, issue 3 ; ISSN 2165-0497 |
بيانات النشر: |
American Society for Microbiology |
سنة النشر: |
2022 |
الوصف: |
Shigellosis is a diarrheal disease that is prevalent in developing countries and especially dangerous in young children. Currently, animal models for shigellosis are unable to model some aspects of the infectious cycle. Here, we describe a new shigellosis model in adult zebrafish, an increasingly common model organism for studying bacterial pathogens. The zebrafish model can be used to study Shigella colonization, transmission, and immune responses, as well as test vaccine efficacy. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1128/spectrum.00347-22 |
الإتاحة: |
https://doi.org/10.1128/spectrum.00347-22Test |
حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ ; https://journals.asm.org/non-commercial-tdm-licenseTest |
رقم الانضمام: |
edsbas.8E07E00E |
قاعدة البيانات: |
BASE |