دورية أكاديمية
Valorisation of Prunus avium L. By-Products: Phenolic Composition and Effect on Caco-2 Cells Viability
| العنوان: | Valorisation of Prunus avium L. By-Products: Phenolic Composition and Effect on Caco-2 Cells Viability |
|---|---|
| المؤلفون: | Nunes, Ana R., Gonçalves, Ana C., Alves, Gilberto, Falcão, Amílcar, Garcia-Viguera, Cristina, A Moreno, Diego, Silva, Luís R |
| بيانات النشر: | MDPI |
| سنة النشر: | 2021 |
| المجموعة: | Universidade de Coimbra: Estudo Geral |
| مصطلحات موضوعية: | Prunus avium L, by-products, phenolic compounds, antiproliferative properties |
| الوصف: | Prunus avium L. by-products, such as stems, leaves, and flowers, are used in folk medicine to prevent and treat some diseases. However, their phenolic composition and in vitro bioactivities against tumor cells are poorly known. In this work, we compared the phenolic profile and the biological potential of aqueous infusions and hydroethanolic extracts of P. avium leaves, stems, and flowers from Saco cultivar, collected from the Fundão region (Portugal). Among the fifty-two phenolic compounds tentatively identified by HPLC-DAD-ESI/MSn, the hydroxycinnamic acids were the most abundant. Both extracts of stems revealed a higher activity against DPPH•. Meanwhile, hydroethanolic extracts from stems and flowers and aqueous infusions of flowers were the most effective in inhibiting the growth of the human epithelial colorectal adenocarcinoma (Caco-2) cells at concentrations above 200 μg/mL. More detailed knowledge about the phenolic composition and health-promoting properties of Portuguese P. avium by-products allows for increasing the biological and commercial value of these bio-wastes, which may have a positive impact on food and pharmaceutical industries, as on the valorization of the local economy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2304-8158 |
| العلاقة: | #PLACEHOLDER_PARENT_METADATA_VALUE#; SFRH/BD/139137/2018; POCI-01-0145-FEDER-007491; CENTRO-01-0247-FEDER- 017547; Fundación Seneca, Murcia Regional Agency for Science and Technology, Project 19900/GERM/15 at CEBAS-CSIC; http://hdl.handle.net/10316/103952Test |
| DOI: | 10.3390/foods10061185 |
| الإتاحة: | https://doi.org/10.3390/foods10061185Test http://hdl.handle.net/10316/103952Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8C9D40BE |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23048158 |
|---|---|
| DOI: | 10.3390/foods10061185 |