NON-INVASIVE ASSESSMENT OF THE PULMONARY AND SYSTEMIC VASCULAR DISTENSIBILITY AT EXERCISE IN SEDENTARY VS. ATHLETIC SUBJECTS

التفاصيل البيبلوغرافية
العنوان: NON-INVASIVE ASSESSMENT OF THE PULMONARY AND SYSTEMIC VASCULAR DISTENSIBILITY AT EXERCISE IN SEDENTARY VS. ATHLETIC SUBJECTS
المؤلفون: Carpentier, Marine, Motoji, Yoshiki, Selvais, Nicolas, Rabineau, Jérémy, Tordeur, Cyril, Forton, Kevin, Chaumont, Martin, Faoro, Vitalie
المساهمون: European Congress of Sport Science (ECSS) (05-07/07/2023: Paris, France)
سنة النشر: 2023
المجموعة: DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB)
مصطلحات موضوعية: Cardiologie et circulation, pulmonary vascular distensibility, systemic compliance
الوصف: INTRODUCTIONPhysical activity improves cardio-vascular health condition. However, it remains uncertain how much training affects the vascular distensibility (α) of the pulmonary circulation, especially regarding to the systemic vascular distensibility. This is of particular interest as the right ventricle (RV) function is under heavy stress during exercise (1) at high cardiac output (Q) and a more distensible circulation would smoothen the RV afterload. We therefore compared the RV and pulmonary circulation response at exercise among athletes and sedentary subjects, with the exercise systemic vascular response. METHODS17 professional football players (24±3 years) matched (age and body mass index) with 17 sedentary volunteers, performed an incremental cyclo-ergometric exercise echocardiography for RV and pulmonary circulation evaluation. Gas exchanges and systemic arterial blood pressure were measured continuously during exercise. Q was calculated from the left ventricular outflow tract flow velocity-time integral, mean pulmonary arterial pressure (mPAP) was calculated from the peak tricuspid regurgitation velocity and right atrial pressure. The coupling of RV function to the pulmonary circulation was evaluated by the tricuspid annular plane systolic excursion (TAPSE) to systolic PAP (PAPs) ratio. Pulmonary and systemic vascular distensibility, αpulm and αsys, were determined from multi-point mPAP/atrial pressure vs Q relationships, established by Linehan equation (2).RESULTSWhile athletes displayed smoothened chronotropic (HR) (p<0.001) and enhanced inotropic (p=0.006) response to exercise as compared to sedentary subjects, the exercise-induced increase in PAPm or the decrease in TAPSE/PAPs did not differ between the two groups. However, αpulm was higher in athletes than in sedentary people (1.37±0.41 vs 0.88±0.42%/mmHg, p=0.002) and correlated, at identical exercise intensity, with the TAPSE/PAPs ratio (football players: p=0.006, r=0.63, sedentary: p<0.001, r=0.79). αsys was correlated to αpulm ...
نوع الوثيقة: conference object
وصف الملف: 1 full-text file(s): application/pdf
اللغة: English
العلاقة: https://dipot.ulb.ac.be/dspace/bitstream/2013/360818/3/Carpentier.ECSS.2023.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/360818Test
الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/360818Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/360818/3/Carpentier.ECSS.2023.pdfTest
رقم الانضمام: edsbas.8BAE65FF
قاعدة البيانات: BASE