التفاصيل البيبلوغرافية
| العنوان: |
Influence of aortic regurgitation after TAVI on left ventricular filling pattern |
| المؤلفون: |
Caballero, Luis, Saura, Daniel, García‐Lara, Juan, Oliva, Maria José, Pinar, Eduardo, González‐Carrillo, Josefa, García‐Navarro, Miguel, Espinosa, Maria Dolores, Valdés, Mariano, de la Morena, Gonzalo |
| المصدر: |
European Journal of Clinical Investigation ; volume 45, issue 1, page 18-26 ; ISSN 0014-2972 1365-2362 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2014 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Background Paravalvular aortic regurgitation after transcatheter aortic valve implantation is associated with a hemodynamic deterioration and a poor outcome. We aim to determine the early hemodynamic effect of paravalvular aortic regurgitation in relation with the change in the left ventricle filling pattern and to assess their clinical outcome. Material and methods Eighty‐two consecutive patients referred for transcatheter aortic valve implantation were included. Patients were classified according to the change in the left ventricular filling pattern, and significant paravalvular aortic regurgitation (grade ≥ 2) was reported. Follow‐up and incidence of death and hospitalization for heart failure were reported. Results Sixteen patients (19·5%) presented a worsening of left ventricular filling pattern. The incidence of significant paravalvular aortic regurgitation was higher in the group with a worsening of left ventricular filling pattern (56·3% vs. 19·7%; P = 0·009). In the multivariate analysis, the only variable significantly associated with the worsening of left ventricular filling pattern was the significant paravalvular aortic regurgitation ( OR 4·84; 95% CI 1·23 – 19·1; P = 0·024). During the follow‐up (642·5 days), there was a higher incidence of the endpoint of death or hospitalization for heart failure in the group with a worsening of left ventricular filling pattern (62·5% vs. 31·8%; P = 0·042) and a lower event‐free survival rate (long rank test = 0·013). Conclusions The presence of a significant paravalvular aortic regurgitation is associated with a worsening in parameters of diastolic function. This finding should alert the cardiologist as patients with a worsening of left ventricular filling pattern present a higher incidence of paravalvular aortic regurgitation and a less favourable outcome. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/eci.12374 |
| الإتاحة: |
https://doi.org/10.1111/eci.12374Test |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.8673FEF9 |
| قاعدة البيانات: |
BASE |
