دورية أكاديمية
Continuous vs Bolus Thermodilution to Assess Microvascular Resistance Reserve.
| العنوان: | Continuous vs Bolus Thermodilution to Assess Microvascular Resistance Reserve. |
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| المؤلفون: | Gallinoro, E., Bertolone, D.T., Mizukami, T., Paolisso, P., Bermpeis, K., Munhoz, D., Sakai, K., Seki, R., Ohashi, H., Esposito, G., Caglioni, S., Mileva, N., Leone, A., Candreva, A., Belmonte, M., Storozhenko, T., Viscusi, M.M., Vanderheyden, M., Wyffels, E., Bartunek, J., Sonck, J., Barbato, E., Collet, C., De Bruyne, B. |
| المصدر: | JACC. Cardiovascular interventions, vol. 16, no. 22, pp. 2767-2777 |
| سنة النشر: | 2023 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | Humans, Coronary Circulation, Fractional Flow Reserve, Myocardial, Thermodilution/methods, Reproducibility of Results, Treatment Outcome, Coronary Vessels, Microcirculation, CFR, FFR, angina, coronary artery disease, coronary flow, microvascular dysfunction |
| الوصف: | Coronary flow reserve (CFR) and microvascular resistance reserve (MRR) can, in principle, be derived by any method assessing coronary flow. The aim of this study was to compare CFR and MRR as derived by continuous (CFR cont and MRR cont ) and bolus thermodilution (CFR bolus and MRR bolus ). A total of 175 patients with chest pain and nonobstructive coronary artery disease were studied. Bolus and continuous thermodilution measurements were performed in the left anterior descending coronary artery. MRR was calculated as the ratio of CFR to fractional flow reserve and corrected for changes in systemic pressure. In 102 patients, bolus and continuous thermodilution measurements were performed in duplicate to assess test-retest reliability. Mean CFR bolus was higher than CFR cont (3.47 ± 1.42 and 2.67 ± 0.81 [P < 0.001], mean difference 0.80, upper limit of agreement 3.92, lower limit of agreement -2.32). Mean MRR bolus was also higher than MRR cont (4.40 ± 1.99 and 3.22 ± 1.02 [P < 0.001], mean difference 1.2, upper limit of agreement 5.08, lower limit of agreement -2.71). The correlation between CFR and MRR values obtained using both methods was significant but weak (CFR, r = 0.28 [95% CI: 0.14-0.41]; MRR, r = 0.26 [95% CI: 0.16-0.39]; P < 0.001 for both). The precision of both CFR and MRR was higher when assessed using continuous thermodilution compared with bolus thermodilution (repeatability coefficients of 0.89 and 2.79 for CFR cont and CFR bolus , respectively, and 1.01 and 3.05 for MRR cont and MRR bolus , respectively). Compared with bolus thermodilution, continuous thermodilution yields lower values of CFR and MRR accompanied by an almost 3-fold reduction of the variability in the measured results. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1936-8798 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/38030361; info:eu-repo/semantics/altIdentifier/eissn/1876-7605; https://serval.unil.ch/notice/serval:BIB_681376CA1588Test; urn:issn:1936-8798 |
| DOI: | 10.1016/j.jcin.2023.09.027 |
| الإتاحة: | https://doi.org/10.1016/j.jcin.2023.09.027Test https://serval.unil.ch/notice/serval:BIB_681376CA1588Test |
| رقم الانضمام: | edsbas.85FF8373 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19368798 |
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| DOI: | 10.1016/j.jcin.2023.09.027 |