دورية أكاديمية
The microvascular endothelial glycocalyx:An additional piece of the puzzle in veterinary medicine
| العنوان: | The microvascular endothelial glycocalyx:An additional piece of the puzzle in veterinary medicine |
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| المؤلفون: | Lawrence-Mills, Sara, Hughes, David, Hezzell, Melanie J, Butler, Matthew J, Neal, Chris R, Foster, R R, Welsh, Gavin I, Finch, Natalie C |
| المصدر: | Lawrence-Mills , S , Hughes , D , Hezzell , M J , Butler , M J , Neal , C R , Foster , R R , Welsh , G I & Finch , N C 2022 , ' The microvascular endothelial glycocalyx : An additional piece of the puzzle in veterinary medicine ' , Veterinary Journal , vol. 285 , 105843 . https://doi.org/10.1016/j.tvjl.2022.105843Test |
| سنة النشر: | 2022 |
| المجموعة: | University of Bristol: Bristol Reserach |
| مصطلحات موضوعية: | Detection, Diagnosis, Disease, Physiology, Visualisation |
| الوصف: | The endothelial glycocalyx (eGlx) is a critically important structure lining the luminal surface of endothelial cells. There is increasing evidence, in human patients and animal models, for its crucial role in the maintenance of health. Moreover, its damage is associated with the pathogenesis of multiple disease states. This review provides readers with an overview of the eGlx; summarising its structure, essential functions, and evidence for its role in disease. We highlight the lack of studies regarding the eGlx in cats and dogs, particularly in naturally occurring diseases. Importantly, we discuss techniques to aid its study, which can be applied to veterinary species. Finally, we present targeted therapies aimed at preserving, and in some cases, restoring damaged eGlx. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1016/j.tvjl.2022.105843 |
| الإتاحة: | https://doi.org/10.1016/j.tvjl.2022.105843Test https://hdl.handle.net/1983/c6c9ef03-322c-457b-85f4-a983ad0243dbTest https://research-information.bris.ac.uk/en/publications/c6c9ef03-322c-457b-85f4-a983ad0243dbTest https://research-information.bris.ac.uk/ws/files/326615011/1_s2.0_S1090023322000582_main.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.85C3F8CA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.tvjl.2022.105843 |
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