دورية أكاديمية
Factors Predicting Change in Frequency of Heavy Drinking Days among Alcohol-Dependent Participants in the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
| العنوان: | Factors Predicting Change in Frequency of Heavy Drinking Days among Alcohol-Dependent Participants in the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) |
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| المؤلفون: | Sarsour, Khaled, Johnston, Joseph A., Milton, Denái R., Duhig, Amy, Melfi, Catherine, Moss, Howard B. |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2012 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | TREATMENT |
| الوصف: | Aims: To discover the predictors of change in the frequency of heavy drinking (HD) over a 4-year period in alcohol dependent (AD)-individuals identified in the general population, namely, among participants of the US National Epidemiologic Survey on Alcohol and Related Conditions interviewed at Wave 1 (2001–2002) and at Wave 2 (2004–2005). Methods: The study cohort included subjects meeting DSM-IV criteria for AD in the past year at Wave 1 ( n = 1484), who were present at Wave 2 ( n = 1172) and had complete data on factors of interest ( n = 1123). Frequency of HD was defined as the number of HD days (HDD) (≥5 drinks per day for men and ≥4 for women). Change in frequency of HDD from baseline (Wave 1) to ∼3 years later (Wave 2) was determined. An analysis of covariance model (ANCOVA), adjusting for baseline HDD, was used to examine individual factors associated with change in frequency of HDD, while a multivariable regression model was employed to assess factors associated with change in frequency of HDD simultaneously. Results: Overall, there was a decrease in mean (SE) HDD [from 119.4 (1.8) at Wave 1 to 82.5 (2.1) at Wave 2, P < 0.0001]. Compared with smokers, non-smokers had a mean (SE) HDD reduction of 13.4 (6.7), P < 0.05. AD criteria of tolerance was significantly associated ( P < 0.05) with less reduction in HDD. Change in depression/dysthymia status was associated with greater reduction in HDD in the ANCOVA model, but not the fully adjusted multivariable model. Conclusion: Findings from this study suggest that smoking and AD criteria of tolerance are important factors for long-term follow-up of AD patients and they should influence the selection of the kinds of interventions required for AD patients to achieve maximal therapeutic benefit. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://alcalc.oxfordjournals.org/cgi/content/short/47/4/443Test; http://dx.doi.org/10.1093/alcalc/ags036Test |
| DOI: | 10.1093/alcalc/ags036 |
| الإتاحة: | https://doi.org/10.1093/alcalc/ags036Test http://alcalc.oxfordjournals.org/cgi/content/short/47/4/443Test |
| حقوق: | Copyright (C) 2012, Medical Council on Alcohol |
| رقم الانضمام: | edsbas.845A4E39 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/alcalc/ags036 |
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