دورية أكاديمية
Fungal Burden and Raised Intracranial Pressure Are Independently Associated With Visual Loss in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis
| العنوان: | Fungal Burden and Raised Intracranial Pressure Are Independently Associated With Visual Loss in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis |
|---|---|
| المؤلفون: | Molloy, SF, Ross, B, Kanyama, C, Mfinanga, S, Lesikari, S, Heyderman, RS, Kalata, N, Ellis, J, Kouanfack, C, Chanda, D, Temfack, E, Lakhi, S, Moodley, A, Chan, AK, van Oosterhout, JJ, Mapoure, Y, Mwaba, P, Lalloo, DG, Wang, D, Lortholary, O, Jaffar, S, Hosseinipour, MC, Loyse, A, Harrison, TS, Bicanic, T |
| المصدر: | Open Forum Infectious Diseases , 8 (4) , Article ofab066. (2021) |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2021 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Cryptococcal meningitis, fungal burden, HIV, raised intracranial pressure, visual loss |
| الوصف: | Among 472 patients with human immunodeficiency virus-associated cryptococcal meningitis, 16% had severe visual loss at presentation, and 46% of these were 4-week survivors and remained severely impaired. Baseline cerebrospinal fluid opening pressure ≥40 cmH2O (adjusted odds ratio [aOR], 2.56; 95% confidence interval [CI], 1.36–4.83; P = .02) and fungal burden >6.0 log10 colonies/mL (aOR, 3.01; 95% CI, 1.58–5.7; P = .003) were independently associated with severe visual loss. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://discovery.ucl.ac.uk/id/eprint/10127412/1/ofab066.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10127412Test/ |
| الإتاحة: | https://discovery.ucl.ac.uk/id/eprint/10127412/1/ofab066.pdfTest https://discovery.ucl.ac.uk/id/eprint/10127412Test/ |
| حقوق: | open |
| رقم الانضمام: | edsbas.828AF766 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |