دورية أكاديمية

Gender differences in quality of life in adults with long-standing type 1 diabetes mellitus

التفاصيل البيبلوغرافية
العنوان: Gender differences in quality of life in adults with long-standing type 1 diabetes mellitus
المؤلفون: Castellano Guerrero, Ana María, Guerrero, Raquel, Ruiz Aranda, Desireé, Perea, Sofía, Pumar, Alfonso, Relimpio, Federico, Mangas, Miguel Ángel, Losada, Fernando, Martínez Brocca, María Asunción
سنة النشر: 2020
مصطلحات موضوعية: Gender differences, Quality of life, Type 1 diabetes mellitus
الوصف: Background To assess gender differences in Quality of life (QoL) and in sociodemographic, clinical and psychological factors associated with impaired QoL in adults with long-standing type 1 diabetes mellitus (DM1). Methods Cross-sectional evaluation in a random cohort of DM1 adult patients from a tertiary care hospital. QoL was evaluated using translated and validated self-administered Diabetes QoL questionnaire (Es-DQoL), and results transformed into a 0–100 scale. Psychological assessment included a planned psychological interview and self-reported questionnaires (Beck Depression Inventory II, State-Trait Anxiety Inventory Form Y, Fear of hypoglycaemia Scale, Medical Outcomes Study Social Support Survey). Results A total of 312 patients (51.6% male; 38.2 ± 12.7 years; HbA1c 7.5 ± 1.1% (58.5 ± 14.2 mmol/mol); 20.4 ± 12.0 years of DM1) were included in the analysis. Male and female subgroups showed similar sociodemographic and diabetes-related features and comparable social support. Among female patients, higher frequency of depression [31.7% (IC95% 26.2–40.8) vs. 14.9% (IC95% 10.1–20.8), p < 0.05] and anxiety [23.2% (IC95% 19.3–33.14) vs. 13.0% (IC95% 8.1–18.4), p < 0.05] and severity of depressive and anxious symptoms were also found. Compared to male patients, female patients showed lower QoL [75 (IC95% 73.6–77.5) vs. 80 (IC95% 75.7–83.1), p < 0.05] and scored significantly worse in subscale Diabetes-related worries [69 (IC95% 50.0–81.0) vs. 75 (IC95% 72.9–79.0), p < 0.05]. Fear of hypoglycemia and severity of depressive and anxious symptoms were factors independently associated to lower QoL in men and women while high frequency of glycemic excursions was a female-specific predictive one. Conclusions Adult women with long-standing DM1 showed lower QoL probably related to higher frequency and severity of psychopathological syndromes. Depressive and anxious symptoms and, among women, exposure to glycemic excursions were identified as modifiable, QoL-related variables. Educational, technological and ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1758-5996
العلاقة: Project “PI17/01674”, funded by Instituto de Salud Carlos III and co-funded by European Union (ERDF/ESF, “Investing in your future”).; Castellano-Guerrero, A.M., Guerrero, R., Ruiz-Aranda, D. et al. Gender differences in quality of life in adults with long-standing type 1 diabetes mellitus. Diabetol Metab Syndr 12, 64 (2020). https://doi.org/10.1186/s13098-020-00571-xTest; https://hdl.handle.net/20.500.12412/4577Test
DOI: 10.1186/s13098-020-00571-x
الإتاحة: https://doi.org/20.500.12412/4577Test
https://doi.org/10.1186/s13098-020-00571-xTest
https://hdl.handle.net/20.500.12412/4577Test
حقوق: Attribution-NonCommercial-NoDerivatives 4.0 Internacional ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; openAccess
رقم الانضمام: edsbas.81B4AD8B
قاعدة البيانات: BASE
الوصف
تدمد:17585996
DOI:10.1186/s13098-020-00571-x