دورية أكاديمية
Different Statin Effects of ST-elevation Versus Non-ST-Elevation Acute Myocardial Infarction After Stent Implantation
| العنوان: | Different Statin Effects of ST-elevation Versus Non-ST-Elevation Acute Myocardial Infarction After Stent Implantation |
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| المساهمون: | Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Ko, Young Guk |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Aged, Drug-Eluting Stents / statistics & numerical data, Humans, Middle Aged, Non-ST Elevated Myocardial Infarction / epidemiology, Non-ST Elevated Myocardial Infarction / etiology, Non-ST Elevated Myocardial Infarction / mortality, Percutaneous Coronary Intervention / statistics & numerical data, Republic of Korea / epidemiology, ST Elevation Myocardial Infarction / epidemiology, ST Elevation Myocardial Infarction / etiology, ST Elevation Myocardial Infarction / mortality, Cardiovascular outcomes, Non-ST-segment elevation myocardial infarction, Statins, ST-segment elevation myocardial |
| الوصف: | Background: Intensive statin therapy reduces cardiovascular events in acute coronary syndrome. The data concerning the long-term clinical impacts of statin therapy between ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) after drug-eluting stent implantation are limited. We compared the 2-year clinical outcomes between these 2 groups after statin therapy. Materials and Methods: A total of 30,616 Korean patients with acute myocardial infarction (AMI) were enrolled. Among them, 13,686 patients were classified as group A (STEMI statin user), 3,824 patients were as group B (STEMI statin nonuser), 10,398 patients were as group C (NSTEMI statin user), and 2,708 patients were as group D (NSTEMI statin nonuser). The major clinical endpoint was the occurrence of major adverse cardiac events (MACE) defined as all-cause death, recurrent myocardial infarction (re-MI), and any repeat revascularization during a 2-year follow-up period. Results: After adjustment, the cumulative risks of MACE (adjusted hazard ratio [aHR] = 1.112 [1.002-1.235]; P = 0.047), all-cause death (aHR = 1.271 [1.054-1.532]; P = 0.012), and target vessel revascularization (TVR, aHR = 1.262 [1.049-1.518]; P = 0.014) in group C were significantly higher than group A. The cumulative risks of MACE, all-cause death, and cardiac death of the statin nonuser group (groups B and D) were significantly higher compared with statin user group (groups A and C). Conclusions: Statin therapy was more effective in reducing the cumulative risks of MACE, all-cause death, and TVR in the STEMI group than NSTEMI group in Korean patients with AMI after successful drug-eluting stent implantation. ; restriction |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0002-9629 1538-2990 |
| العلاقة: | AMERICAN JOURNAL OF THE MEDICAL SCIENCES; J04258; OAK-2022-03855; OAK-2022-03856; OAK-2022-03857; OAK-2022-03858; OAK-2022-03859; OAK-2022-03860; OAK-2022-03861; OAK-2022-03862; https://ir.ymlib.yonsei.ac.kr/handle/22282913/190201Test; https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0002962919304288Test; T9992020426; AMERICAN JOURNAL OF THE MEDICAL SCIENCES, Vol.359(3) : 156-167, 2020-03 |
| DOI: | 10.1016/j.amjms.2019.12.004 |
| الإتاحة: | https://doi.org/10.1016/j.amjms.2019.12.004Test https://ir.ymlib.yonsei.ac.kr/handle/22282913/190201Test https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0002962919304288Test |
| حقوق: | CC BY-NC-ND 2.0 KR |
| رقم الانضمام: | edsbas.8106ABA1 |
| قاعدة البيانات: | BASE |
| تدمد: | 00029629 15382990 |
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| DOI: | 10.1016/j.amjms.2019.12.004 |